UPF3B / RENT3B antibody

Principal name

UPF3B / RENT3B antibody

Alternative names for UPF3B / RENT3B antibody

UPF3X, hUpf3p-X, Up-frameshift suppressor 3 homolog B, Regulator of nonsense transcripts 3B, Nonsense mRNA reducing factor 3B

SwissProt ID

Q9BZI7 (Human)

Gene ID

65109 (UPF3B)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Frozen Sections (C)

Background of UPF3B / RENT3B antibody

UPF3B is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The protein is one of two functional homologs to yeast Upf3p. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome X. Two splice variants encoding different isoforms have been found for this gene.

General readings

Chamieh,H., (2008) Nat. Struct. Mol. Biol. 15 (1), 85-93

11 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

UPF3B / RENT3B antibody

WB Suggested Anti-UPF3B Antibody Titration: 1.25 ug/ml; ELISA Titer: 1: 312500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Hu, Ms, Por, Rb, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

UPF3B / RENT3B antibody

WB Suggested Anti-UPF3B Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Human heart Rabbit IgG Purified Can, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

UPF3B / RENT3B antibody

Human Stomach; Rabbit Anti-UPF3B Antibody. Catalog Number: ARP40998. Paraffin Embedded Tissue: Human Stomach. Cellular Data: Epithelial cells of fundic gland. Antibody Concentration: 4.0-8.0 ug/ml. Magnification: 400X; UPF3B antibody - N-terminal region (ARP40998_T100) in Human Stomach cells using Immunohistochemistry Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

UPF3B / RENT3B antibody

Human Heart; WB Suggested Anti-UPF3B Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human heart; UPF3B antibody - middle region (ARP41088_P050) in Human Heart cells using Western Blot Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

UPF3B / RENT3B antibody

UPF3B / RENT3B Rabbit Purified Can, Hu P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

UPF3B / RENT3B antibody

Western Blot: UPF3B Antibody [NBP1-57233] - This Anti-UPF3B antibody was used in Western Blot of Fetal Heart tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

UPF3B / RENT3B antibody

Immunohistochemistry-Paraffin: UPF3B Antibody [NBP1-83134] - Immunohistochemical staining of human placenta shows moderate cytoplasmic positivity in trophoblastic and decidual cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

UPF3B / RENT3B antibody

Immunohistochemistry-Paraffin: UPF3B Antibody [NBP1-83135] - Immunohistochemical staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells. Rabbit IgG Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

UPF3B / RENT3B

UPF3B / RENT3B Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates (Overexpressed)

Catalog No.    

UPF3B overexpression lysate

UPF3B overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

UPF3B overexpression lysate

UPF3B overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

11 Item(s)

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