Uracil-DNA glycosylase (UNG) antibody

Principal name

Uracil-DNA glycosylase (UNG) antibody

Alternative names for Uracil-DNA glycosylase (UNG) antibody

UDG, DGU, UNG1, UNG15

SwissProt ID

P13051 (Human)

Gene ID

7374 (UNG)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Por (Porcine), Mky (Monkey), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)

Background of Uracil-DNA glycosylase (UNG) antibody

The human UNG gene encodes both nuclear (UNG2) and mitochondrial (UNG1) forms of uracil-D glycosylase. These forms are generated by altertive splicing and the use of two differentially regulated promoters, PA and PB (Slupphaug et al., 1993; Nilsen et al., 1997) The cDs for UNG1 and UNG2 are of similar size (2061 and 2058 bp, respectively) and as a result the corresponding mRs are not resolved as two species in gel electrophoresis (Huag et al., 1998). Nuclear UNG2 differs from mitochondrial UNG1 in 44 amino acids of the N-termil sequence that is not necessary for catalytic activity. A major role of the UNG gene products is to repair mutagenic U:G mispairs caused by cytosine deamition. For example, UNG2 removes misincorporated dUMP residues. The level and expression pattern of UNG1 and UNG2 differs between cell and tissue type (Huag et al. 1998). Additiolly, the expression of UNG is cell cycle regulated (gelhus et al. 1995). The expression and activity of UNG has been found in general to be higher in proliferating as compared to nonproliferating tissues and cells (reviewed in Kruman et al. 2004). UNG1 is a 304 amino acid protein. UNG2 is a 313 amino acid protein.

General readings

Jau der C et al.,(1991) J Bacteriol 173(1):283?290
Haug T et al.,(1998) Nucleic Acids Res. 26(6):1449?1457
Hilde N et al.,(2000) Nucleic Acids Res. 28(12):2277?2285
Stuart R.W et al.,(2007) Nucleic Acids Res. 35(5):1478?1487
Chih chung L et al.,(2007) J Virol 81(3):1195?1208

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Uracil-DNA glycosylase (UNG) antibody

Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-UNG mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503563) Mouse IgG2b OTI2C12 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Uracil-DNA glycosylase (UNG) antibody

Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-UNG mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503499) Mouse IgG1 OTI1G1 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Uracil-DNA glycosylase (UNG) antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-UNG mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503513) Mouse IgG1 OTI1A11 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Uracil-DNA glycosylase (UNG) antibody

Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-UNG mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503533) Mouse IgG1 OTI1B6 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Uracil-DNA glycosylase (UNG) antibody

Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-UNG mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503534) Mouse IgG2a OTI2F8 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Uracil-DNA glycosylase (UNG) antibody

Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-UNG mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503613) Mouse IgG2a OTI1F8 Purified Hu F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Uracil-DNA glycosylase (UNG) antibody

Immunohistochemical staining of paraffin-embedded Human endometrium tissue within the normal limits using anti-UNG mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503755) Mouse IgG2b OTI1G2 Purified Hu, Mky P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

Uracil-DNA glycosylase (UNG) antibody

Immunohistochemistry: AM09040PU-N UNG antibody staining of Formalin-Fixed, Paraffin-Embedded Human Thymus at 10 µg/ml followed by biotinylated anti-Mouse IgG secondary antibody, Alkaline Phosphatase-Streptavidin and chromogen. Mouse IgG2b k1C12 Purified Hu E, P, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

Uracil-DNA glycosylase (UNG) antibody

Immunohistochemistry: AM09040PU-N UNG antibody staining of Formalin-Fixed, Paraffin-Embedded Human Thymus at 10 µg/ml followed by biotinylated anti-Mouse IgG secondary antibody, Alkaline Phosphatase-Streptavidin and chromogen. Mouse IgG2b k1C12 Purified Hu E, P, WB
50 µl / €230.00
  Acris Antibodies GmbH

Uracil-DNA glycosylase (UNG) (C-term) antibody

Western blot analysis of UNG1 in C2C12 cell lysate with UNG1 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Uracil-DNA glycosylase (UNG) (N-term) antibody

Western blot analysis of UNG1 in C2C12 cell lysate with UNG1 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Uracil-DNA glycosylase (UNG) antibody

Western blot analysis of extracts from HepG2 cells and COLO cells, using UNG antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Uracil-DNA glycosylase (UNG) antibody

Western blot analysis of UNG2 in 3T3 cell lysate with UNG2 antibody at 1 ug/mL in (A) the presence and (B) the absence of blocking peptide. Rabbit IgG Purified Hu, Ms ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Uracil-DNA glycosylase (UNG) antibody

Western Blot: uracil-DNA glycosylase Antibody [TA336670] - Analysis of UNG in HeLa cell lysate with using this antibody at 2 ug/ml. Rabbit Purified Hu, Ms, Rb, Rt ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Uracil-DNA glycosylase (UNG) antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY UNG (RC222868, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-UNG. Mouse IgG1 OTI1A6 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Uracil-DNA glycosylase (UNG) antibody

Anti-UNG mouse monoclonal antibody (TA503567) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY UNG(RC222868). Mouse IgG2a OTI2F3 Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Uracil-DNA glycosylase (UNG) antibody

Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-UNG mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503618) Mouse IgG1 OTI2B5 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Uracil-DNA glycosylase (UNG) (C-term) antibody

Immunohistochemical staining of human heart with Rabbit anti Human uracil-DNA glycosylase 1 (AP05613PU-N) Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €330.00
  Acris Antibodies GmbH

Uracil-DNA glycosylase (UNG) antibody

Formalin-Fixed Paraffin-Embedded Human Kidney stained with Uracil-DNA glycosylase / UNG Antibody Cat.-No AP07386PU-N at 5 µg/ml  after heat-induced antigen retrieval. Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Uracil-DNA glycosylase (UNG) antibody

Figure 2. Staining UNG in Testis by Immunohistochemistry using Formalin-Fixed Paraffin-Embedded (FFPE) tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

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