Uracil-DNA glycosylase (UNG) antibody

Principal name

Uracil-DNA glycosylase (UNG) antibody

Alternative names for Uracil-DNA glycosylase (UNG) antibody

UDG, DGU, UNG1, UNG15

SwissProt ID

P13051 (Human)

Gene ID

7374 (UNG)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Por (Porcine), Mky (Monkey), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)

Background of Uracil-DNA glycosylase (UNG) antibody

The human UNG gene encodes both nuclear (UNG2) and mitochondrial (UNG1) forms of uracil-D glycosylase. These forms are generated by altertive splicing and the use of two differentially regulated promoters, PA and PB (Slupphaug et al., 1993; Nilsen et al., 1997) The cDs for UNG1 and UNG2 are of similar size (2061 and 2058 bp, respectively) and as a result the corresponding mRs are not resolved as two species in gel electrophoresis (Huag et al., 1998). Nuclear UNG2 differs from mitochondrial UNG1 in 44 amino acids of the N-termil sequence that is not necessary for catalytic activity. A major role of the UNG gene products is to repair mutagenic U:G mispairs caused by cytosine deamition. For example, UNG2 removes misincorporated dUMP residues. The level and expression pattern of UNG1 and UNG2 differs between cell and tissue type (Huag et al. 1998). Additiolly, the expression of UNG is cell cycle regulated (gelhus et al. 1995). The expression and activity of UNG has been found in general to be higher in proliferating as compared to nonproliferating tissues and cells (reviewed in Kruman et al. 2004). UNG1 is a 304 amino acid protein. UNG2 is a 313 amino acid protein.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Uracil-DNA glycosylase (UNG) antibody

  UNG mouse monoclonal antibody, clone OTI2C12 (formerly 2C12)  
Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-UNG mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503563) Mouse IgG2b OTI2C12 Purified Hu ICC/IF, P, WB
0.1 ml / €350.00
  OriGene Technologies, Inc.

TrueMAB

Uracil-DNA glycosylase (UNG) antibody

  UNG mouse monoclonal antibody, clone OTI1G1 (formerly 1G1)  
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-UNG mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503499) Mouse IgG1 OTI1G1 Purified Hu ICC/IF, P, WB
0.1 ml / €350.00
  OriGene Technologies, Inc.

TrueMAB

Uracil-DNA glycosylase (UNG) antibody

  UNG mouse monoclonal antibody, clone OTI1A11 (formerly 1A11)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-UNG mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503513) Mouse IgG1 OTI1A11 Purified Hu ICC/IF, P, WB
0.1 ml / €350.00
  OriGene Technologies, Inc.

TrueMAB

Uracil-DNA glycosylase (UNG) antibody

  UNG mouse monoclonal antibody, clone OTI1B6 (formerly 1B6)  
Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-UNG mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503533) Mouse IgG1 OTI1B6 Purified Hu ICC/IF, P, WB
0.1 ml / €350.00
  OriGene Technologies, Inc.

TrueMAB

Uracil-DNA glycosylase (UNG) antibody

  UNG mouse monoclonal antibody, clone OTI2F8 (formerly 2F8)  
Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-UNG mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503534) Mouse IgG2a OTI2F8 Purified Hu ICC/IF, P, WB
0.1 ml / €350.00
  OriGene Technologies, Inc.

TrueMAB

Uracil-DNA glycosylase (UNG) antibody

  UNG mouse monoclonal antibody, clone OTI1F8 (formerly 1F8)  
Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-UNG mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503613) Mouse IgG2a OTI1F8 Purified Hu F, P, WB
0.1 ml / €350.00
  OriGene Technologies, Inc.

TrueMAB

Uracil-DNA glycosylase (UNG) antibody

  UNG mouse monoclonal antibody, clone OTI1G2 (formerly 1G2)  
Immunohistochemical staining of paraffin-embedded Human endometrium tissue within the normal limits using anti-UNG mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503755) Mouse IgG2b OTI1G2 Purified Hu, Mky P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

Uracil-DNA glycosylase (UNG) antibody

Immunohistochemistry: AM09040PU-N UNG antibody staining of Formalin-Fixed, Paraffin-Embedded Human Thymus at 10 µg/ml followed by biotinylated anti-Mouse IgG secondary antibody, Alkaline Phosphatase-Streptavidin and chromogen. Mouse IgG2b k1C12 Purified Hu E, ICC/IF, P, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

Uracil-DNA glycosylase (UNG) antibody

Immunohistochemistry: AM09040PU-N UNG antibody staining of Formalin-Fixed, Paraffin-Embedded Human Thymus at 10 µg/ml followed by biotinylated anti-Mouse IgG secondary antibody, Alkaline Phosphatase-Streptavidin and chromogen. Mouse IgG2b k1C12 Purified Hu E, ICC/IF, P, WB
50 µl / €230.00
  Acris Antibodies GmbH

Uracil-DNA glycosylase (UNG) antibody

  UNG mouse monoclonal antibody, clone OTI1A6 (formerly 1A6)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY UNG (RC222868, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-UNG. Mouse IgG1 OTI1A6 Purified Hu WB
0.1 ml / €350.00
  OriGene Technologies, Inc.

TrueMAB

Uracil-DNA glycosylase (UNG) antibody

  UNG mouse monoclonal antibody, clone OTI2F3 (formerly 2F3)  
Anti-UNG mouse monoclonal antibody (TA503567) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY UNG(RC222868). Mouse IgG2a OTI2F3 Purified Hu ICC/IF, WB
0.1 ml / €350.00
  OriGene Technologies, Inc.

TrueMAB

Uracil-DNA glycosylase (UNG) antibody

  UNG mouse monoclonal antibody, clone OTI2B5 (formerly 2B5)  
Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-UNG mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503618) Mouse IgG1 OTI2B5 Purified Hu ICC/IF, P, WB
0.1 ml / €350.00
  OriGene Technologies, Inc.

TrueMAB

12 Item(s)

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