Uromodulin (UMOD) antibody

Principal name

Uromodulin (UMOD) antibody

Alternative names for Uromodulin (UMOD) antibody

Tamm-Horsfall urinary glycoprotein, THP

SwissProt ID

P07911 (Human), P27590 (Rat), P48733 (Bovin), Q862Z3 (Canfa), Q91X17 (Mouse)

Gene ID

7369 (UMOD)

Available reactivities

Hu (Human), Can (Canine), Ms (Mouse), Rt (Rat), Bov (Bovine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Sheep, Mouse, Rabbit, Goat

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Immunodiffusion (ID), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), EPair for Elisa (EPair), Immunoprecipitation (IP), Radioimmunoassay (R)

Background of Uromodulin (UMOD) antibody

May play a role in regulating the circulating activity of cytokines as it binds to IL-1, IL-2 and TNF with high affinity.Tissue specificity:Synthesized by kidney. Most abundant protein in normal human urine.Involvement in disease:Defects in UMOD are the cause of familial juvenile hyperuricemic nephropathy type 1 (HNFJ1) . HNFJ1 is a renal disease characterized by juvenil onset of hyperuricemia, polyuria, progressive renal failure, and gout. The disease is associated with interstitial pathological changes resulting in fibrosis.Defects in UMOD are the cause of medullary cystic kidney disease type 2 (MCKD2) [MIM:603860]. MCKD2 is a form of tubulointerstitial nephropathy characterized by formation of renal cysts at the corticomedullary junction. It is characterized by adult onset of impaired renal function and salt wasting resulting in end-stage renal failure by the sixth decade.his gene encodes uromodulin, the most abundant protein innormal urine. Its excretion in urine follows proteolytic cleavageof the ectodomain of its glycosyl phosphatidylinosital-anchoredcounterpart that is situated on the luminal cell surface of theloop of Henle. Uromodulin may act as a constitutive inhibitor ofcalcium crystallization in renal fluids. Excretion of uromodulin inurine may provide defense against urinary tract infections causedby uropathogenic bacteria. Defects in this gene are associated withthe autosomal dominant renal disorders medullary cystic kidneydisease-2 (MCKD2) and familial juvenile hyperuricemic nephropathy(FJHN). These disorders are characterized by juvenile onset ofhyperuricemia, gout, and progressive renal failure. While severaltranscript variants may exist for this gene, the full-lengthnatures of only two have been described to date. These tworepresent the major variants of this gene and encode the sameisoform.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Uromodulin (UMOD) antibody

(0.03ug/ml) staining of HeLa lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Uromodulin (UMOD) antibody

Predicted band size: 70 kDa . Positive control: MDA-MB453 cell lysate. Recommended dilution: 1/500-2000. (Gel: 8%SDS-PAGE Lysate: 40 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Uromodulin (UMOD) antibody

Western blot analysis of extracts of various cell lines, using UMOD antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

Uromodulin (UMOD) antibody

WB Suggested Anti-UMOD Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: THP-1 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Uromodulin (UMOD) antibody

WB Suggested Anti-UMOD Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: THP-1 cell lysate Rabbit IgG Purified Bov, Can, Hu, Ms WB
50 µg / €325.00
  OriGene Technologies, Inc.

Uromodulin (UMOD) antibody

Uromodulin (UMOD) Mouse IgG2b 10.32 FITC Can, Hu C, E, ICC/IF, P
0.1 mg / €400.00
  Acris Antibodies GmbH

Uromodulin (UMOD) antibody

Uromodulin (UMOD) Mouse IgG2b 10.32 HRP Can, Hu C, E, ICC/IF, P, R
0.1 mg / €460.00
  Acris Antibodies GmbH

Uromodulin (UMOD) antibody

Uromodulin (UMOD) Mouse IgG2b 10.32 Purified Can, Hu C, E, ICC/IF, P
0.25 mg / €460.00
  Acris Antibodies GmbH

Uromodulin (UMOD) antibody

Uromodulin (UMOD) Mouse IgG2b 10.32 Ascites Can, Hu C, E, ICC/IF, P, R
1 ml / €510.00
  Acris Antibodies GmbH

Uromodulin (UMOD) antibody

Uromodulin (UMOD) Sheep Purified Hu ID
1 ml / €410.00
  Acris Antibodies GmbH

Uromodulin (UMOD) antibody

Uromodulin (UMOD) Sheep Ig Fraction Hu C, E
1 ml / €380.00
  Acris Antibodies GmbH

Uromodulin (UMOD) antibody

Immunoperoxidase of purified MaxPab antibody to UMOD on formalin-fixed paraffin-embedded human kidney. [antibody concentration 3 ug/ml] Mouse Purified Hu E(detection), ICC/IF, P, WB
50 µg / €370.00
  Abnova Taiwan Corp.

Uromodulin (UMOD) antibody

Uromodulin (UMOD) Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

Uromodulin (UMOD) antibody

UMOD MaxPab rabbit polyclonal antibody. Western Blot analysis of UMOD expression in human kidney. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Uromodulin (UMOD) antibody

Uromodulin (UMOD) Mouse IgG2b 3F10 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Uromodulin (UMOD) antibody

Human THP-1; WB Suggested Anti-UMOD Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: THP-1 cell lysate; UMOD antibody - middle region (ARP41436_P050) in Human THP-1 cells using Western Blot Rabbit Aff - Purified Can, Hu WB
50 µg / €350.00
  AVIVA Systems Biology

Uromodulin (UMOD) (C-term) antibody

Uromodulin (UMOD) Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

Uromodulin (UMOD) antibody

Western blot analysis of Uromodulin expression in HEK293T (A); THP1 (B) whole cell lysates. Rabbit Aff - Purified Hu WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

Uromodulin (UMOD) antibody

Western blot analysis of Uromodulin expression in HEK293T (A); THP1 (B) whole cell lysates. Rabbit Aff - Purified Hu WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

Uromodulin (UMOD) antibody

Western blot analysis of Uromodulin expression in HEK293T (A); THP1 (B) whole cell lysates. Rabbit Aff - Purified Hu WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

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