Usherin / USH2A antibody

Principal name

Usherin / USH2A antibody

Alternative names for Usherin / USH2A antibody

Usher syndrome type IIa protein, Usher syndrome type-2A protein

SwissProt ID

O75445 (Human), Q2QI47 (Mouse), Q8K3K1 (Rat)

Gene ID

7399 (USH2A)

Available reactivities

Ze (Zebrafish), Hu (Human), Mky (Monkey), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Frozen Sections (C), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Usherin / USH2A antibody

Usher syndrome, an autosomal recessive heterogeneous disorder, is the most common cause of deafness and blindness in adults and affect 3-6% children born with hearing impairment. The affected individuals have sensory-neural deficiencies at birth and subsequently develop progressive retinitis pigmentosa (RP). Three forms of Usher syndrome have been characterized, Usher Type 1, II and III which can be distinguish based on severity of hearing loss and vestibular involvement. Type I patents are profoundly deaf while type II (most common from of Usher syndrome) patients are mildly deaf but have normal in vestibular responses (1).
Ush2A gene has been mapped on a 1 mega base pair interval between marker D1S474 and AFM144XF2. The Usher 2A gene expresses an extra cellular matrix protein that resembles unconventional Myosin and do not appear to have any un-conventional functional correlations. The human Usher Syndrome 2A (Ush2A) protein has 1272 amino acid (Approximate MW 153 kDa) with several functional domains (Laminin type EGF like domain; Laminin-Type epidermal growth factor like domain and fibronectin type 3 like domain). The protein has a single transmembrane domain that anchor the protein to the cell membrane, the rest of the protein stays outside the cell. The Ush2A protein is approximately 153 kDa (1272 amino acids) with multiple conserved domains that is mainly expressed in RPEs.

9 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Usherin / USH2A control peptide

Usherin / USH2A
0.25 mg / €250.00
  Acris Antibodies GmbH

Usherin / USH2A (N-term) antibody

Usherin / USH2A Rabbit IgG Aff - Purified Hu, Mky, Ms, Rt C, IP, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

Usherin / USH2A control peptide

Usherin / USH2A
0.25 mg / €250.00
  Acris Antibodies GmbH

Usherin / USH2A antibody

Usherin / USH2A Rabbit IgG Aff - Purified Hu, Mky, Ms, Rt C, IP, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

Usherin / USH2A control peptide

Usherin / USH2A
0.25 mg / €250.00
  Acris Antibodies GmbH

Usherin / USH2A (C-term) antibody

Usherin / USH2A Rabbit IgG Aff - Purified Hu, Mky, Ms, Rt C, IP, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

Usherin / USH2A (C-term) antibody

Usherin / USH2A Rabbit Purified Hu C, E, ICC/IF, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

Usherin / USH2A antibody

Usherin / USH2A Rabbit Serum Hu C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

Usherin / USH2A antibody

ELISA: Usher syndrome 2A Antibody [27640002] Rabbit Ze E
50 µg / €430.00
  Novus Biologicals Inc.

9 Item(s)

per page
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