USP19 antibody

Principal name

USP19 antibody

Alternative names for USP19 antibody

Ubiquitin carboxyl-terminal hydrolase 19, ZMYND9, KIAA0891, Ubiquitin-specific-processing protease 19, Ubiquitin thioesterase 19, Deubiquitinating enzyme 19, Zinc finger MYND domain-containing protein 9

SwissProt ID

O94966 (Human), Q3UJD6 (Mouse), Q6J1Y9 (Rat)

Gene ID

10869 (USP19), 71472 (Usp19)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P)

Background of USP19 antibody

Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

USP19 antibody

Immunhistochemistry analysis in human heart tissue (Formalin-fixed, Paraffin-embedded) using USP19 antibody Cat.-No. AP32328PU-N. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
50 µl / €425.00
  OriGene Technologies GmbH

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