USP2 antibody

Principal name

USP2 antibody

Alternative names for USP2 antibody

Ubiquitin carboxyl-terminal hydrolase, 2UBP41, Ubiquitin thioesterase 2,Ubiquitin-specific-processing protease 2, Deubiquitinating enzyme 2, 41 kDa ubiquitin-specific protease

SwissProt ID

O75604 (Human), O88623 (Mouse)

Gene ID

9099 (USP2), 53376 (Usp2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of USP2 antibody

Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

USP2 antibody

  USP2 Rabbit Polyclonal (Internal) Antibody  
USP2 Rabbit Aff - Purified Hu P
50 µg / €400.00
  OriGene Technologies, Inc.

USP2 antibody

  USP2 Rabbit Polyclonal (Internal) Antibody  
USP2 Rabbit Aff - Purified Hu, Ms, Rt P
50 µg / €400.00
  OriGene Technologies, Inc.

USP2 (C-term) antibody

  USP2 Rabbit Polyclonal (C-Terminus) Antibody  
USP2 Rabbit Aff - Purified Hu, Ms P
50 µg / €400.00
  OriGene Technologies, Inc.

USP2 antibody

  Rabbit Polyclonal Anti-USP2 Antibody  
WB Suggested Anti-USP2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Human brain Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

USP2 antibody

  Rabbit Polyclonal Anti-USP2 Antibody  
WB Suggested Anti-USP2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: HCT15 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

USP2 (N-term) antibody

Western Blot analysis using anti-USP2 Pab (Cat.#AP12002PU-N) to detect USP2 in HL60 cell lysate. Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

USP2 (C-term) antibody

(LEFT) The anti-USP2 Antibody (C-term)(Cat.#AP12003PU-N) is used in Western blot to detect USP2 in USP2-transfected HeLa cell lysates. Transfection data is kindly provided by Dr. B. Pierrat from the Novartis Institute for Biomedical Research (Basel, Switzerland). (RIGHT) Western blot analysis of anti-USP2 Antibody (C-term) (Cat.#AP12003PU-N) in HL60 cell line lysates (35ug/lane). USP2 (arrow) was detected using the purified Pab. Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

USP2 (C-term) antibody

(LEFT) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. (RIGHT) Formalin-fixed and paraffin-embedded human testis tissue reacted with USP2 antibody (C-term) (Cat#AP12004PU-N), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

USP2 - human gene knockout kit via CRISPR

USP2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

USP2 - human gene knockout kit via CRISPR

USP2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

USP2 - human gene knockout kit via CRISPR

USP2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Usp2 - mouse gene knockout kit via CRISPR

Usp2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Usp2 - mouse gene knockout kit via CRISPR

Usp2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Usp2 - mouse gene knockout kit via CRISPR

Usp2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Usp2 - mouse gene knockout kit via CRISPR

Usp2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

USP2 (transcript variant 2)

  Recombinant protein of human ubiquitin specific peptidase 2 (USP2), transcript variant 2  
USP2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

USP2 overexpression lysate

USP2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

USP2 overexpression lysate

USP2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Lysates (Knockout)

Catalog No.    

USP2 knockout Cell lysate

USP2 knockout Cell lysate  
0.1 mg / €495.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, USP2 (mGFP-tagged) - Human ubiquitin specific peptidase 2 (USP2), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, USP2 (mGFP-tagged) - Human ubiquitin specific peptidase 2 (USP2), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €990.00
  OriGene Technologies, Inc.

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