USP4 / UNP antibody

Principal name

USP4 / UNP antibody

Alternative names for USP4 / UNP antibody

Ubiquitin carboxyl-terminal hydrolase 4, UNPH, Ubiquitin thioesterase 4, Ubiquitin-specific-processing protease 4, Deubiquitinating enzyme 4, Ubiquitous nuclear protein homolog

SwissProt ID

A6QR55 (Bovin), P35123 (Mouse), Q13107 (Human)

Gene ID

7375 (USP4)

Available reactivities

Hu (Human), GP (Guinea Pig), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of USP4 / UNP antibody

Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.

16 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

USP4 / UNP antibody

  Goat Anti-USP4 / UNP Antibody  
Approx 100kDa band observed in Human Heart lysates (calculated MW of 104kDa according to NP_955475.1). Recommended concentration: 1-3ug/ml. Goat Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

USP4 / UNP antibody

  Rabbit Polyclonal Anti-USP4 Antibody (Internal)  
Thymus: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu P
50 µg / €400.00
  OriGene Technologies, Inc.

USP4 / UNP antibody

  Rabbit Polyclonal Anti-USP4 Antibody (Internal)  
Thymus: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu P
50 µg / €400.00
  OriGene Technologies, Inc.

USP4 / UNP antibody

  Rabbit Polyclonal Anti-USP4 Antibody (N-Terminus)  
Anti-USP4 / UNP antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu P, WB
50 µg / €400.00
  OriGene Technologies, Inc.

USP4 / UNP antibody

  Rabbit Polyclonal Anti-USP4 Antibody  
Host: Rabbit; Target Name: USP4; Sample Tissue: Jurkat Whole Cell lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified GP, Hu, Ms, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

USP4 / UNP (C-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

USP4 / UNP (N-term) antibody

USP4 Antibody (N-term) (AP54490PU-N) western blot analysis in human uterine tumor tissue lysates (35 µg/lane). This demonstrates the USP4 antibody detected the USP4 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

USP4 - human gene knockout kit via CRISPR

USP4 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

USP4 - human gene knockout kit via CRISPR

USP4 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

USP4 - human gene knockout kit via CRISPR

USP4 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

USP4 - human gene knockout kit via CRISPR

USP4 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

USP4 / UNP (transcript variant 1)

  Recombinant protein of human ubiquitin specific peptidase 4 (proto-oncogene) (USP4), transcript variant 1  
USP4 / UNP Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, USP4 (mGFP-tagged) - Human ubiquitin specific peptidase 4 (proto-oncogene) (USP4), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, USP4 (mGFP-tagged) - Human ubiquitin specific peptidase 4 (proto-oncogene) (USP4), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, USP4 (mGFP-tagged)-Human ubiquitin specific peptidase 4 (proto-oncogene) (USP4), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, USP4 (mGFP-tagged)-Human ubiquitin specific peptidase 4 (proto-oncogene) (USP4), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,910.00
  OriGene Technologies, Inc.

Lenti ORF particles, USP4 (Myc-DDK tagged) - Human ubiquitin specific peptidase 4 (proto-oncogene) (USP4), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, USP4 (Myc-DDK tagged) - Human ubiquitin specific peptidase 4 (proto-oncogene) (USP4), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, USP4 (Myc-DDK-tagged)-Human ubiquitin specific peptidase 4 (proto-oncogene) (USP4), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, USP4 (Myc-DDK-tagged)-Human ubiquitin specific peptidase 4 (proto-oncogene) (USP4), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,720.00
  OriGene Technologies, Inc.

16 Item(s)

per page
  • LinkedIn