USP4 / UNP antibody

Principal name

USP4 / UNP antibody

Alternative names for USP4 / UNP antibody

Ubiquitin carboxyl-terminal hydrolase 4, UNPH, Ubiquitin thioesterase 4, Ubiquitin-specific-processing protease 4, Deubiquitinating enzyme 4, Ubiquitous nuclear protein homolog

SwissProt ID

A6QR55 (Bovin), P35123 (Mouse), Q13107 (Human)

Gene ID

7375 (USP4)

Available reactivities

Hu (Human), GP (Guinea Pig), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of USP4 / UNP antibody

Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.

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Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

USP4 / UNP (transcript variant 1)

  Recombinant protein of human ubiquitin specific peptidase 4 (proto-oncogene) (USP4), transcript variant 1  
USP4 / UNP Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €438.00
  OriGene Technologies, Inc.

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