USP45 antibody

Principal name

USP45 antibody

Alternative names for USP45 antibody

Ubiquitin carboxyl-terminal hydrolase 45, Ubiquitin thioesterase 45, Ubiquitin-specific-processing protease 45, Deubiquitinating enzyme 45

SwissProt ID

Q70EL2 (Human), Q8K387 (Mouse)

Gene ID

85015 (USP45), 77593 (Usp45)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of USP45 antibody

The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. A wide range of enzymes facilitate the proteolytic Ub pathway, including USPs (ubiquitin specific peptidases), which are cysteine proteases that are responsible for the release of ubiquitin from a ubiquitylated substrate and precursor fusion proteins. USP45 (Ubiquitin carboxyl-terminal hydrolase 45), also known as Deubiquitinating enzyme 45, is a 819 amino acid protein that is involved in ubiquitin-dependent protein catabolism. USP45 differs from other USPs in that it contains a UBP-type zinc finger, a domain which binds ubiquitin. Although USP45 is broadly expressed, the highest levels can be found in skeletal muscle, spleen and ovary. There are three isoforms of USP45 which are produced as a result of alternative splicing.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

USP45 antibody

  Rabbit polyclonal anti-USP45 antibody  
Western blot analysis of extracts from A549 cells, using USP45 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

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