Vang-like protein 2 (VANGL2) antibody

Principal name

Vang-like protein 2 (VANGL2) antibody

Alternative names for Vang-like protein 2 (VANGL2) antibody

Van Gogh-like protein 2, Strabismus 1, STB1, KIAA1215, Loop-tail protein 1 homolog

SwissProt ID

P84889 (Rat), Q91ZD4 (Mouse), Q9ULK5 (Human)

Gene ID

57216 (VANGL2)

Available reactivities

Bov (Bovine), Hu (Human), Ms (Mouse), Ze (Zebrafish), Rt (Rat)

Available hosts

Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P)

Background of Vang-like protein 2 (VANGL2) antibody

The Vang family of proteins are integral membrane proteins that are homologs of the Drosophila tissue polarity gene strabismus. The gene encoding for Van Gogh-like protein 1 (Vangl1), also designated Strabismus 2 (STB2), localizes to chromosome 1p11-p13.1. Van Gogh-like protein 2 (Vangl2), also designated Strabismus1 (STB1), localizes on chromosome 1q22-q23. Vangl1 is expressed in testis and ovary, but also in gastric and pancreatic cancer. Vangl proteins play a key developmental role in establishing planar cell polarity (PCP) and in regulating convergent extension (CE) movements during embryogenesis. Vangl1 and Vangl2 are both down-regulated in several cancer cell lines and primary tumors.Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process.

General readings

Kibar Z, Vogan KJ, Groulx N, Justice MJ, Underhill DA, Gros P.
Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail.
Nat Genet. 2001 Jul;28(3):251-5.
PMID: 11431695

7 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Vang-like protein 2 (VANGL2) antibody

TA303193 (0.3µg/ml) staining of Mouse Brain lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Vang-like protein 2 (VANGL2) antibody

Predicted band size: 60 kDa. Positive control: NIH/3T3 cell lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/250 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 2 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Vang-like protein 2 (VANGL2) antibody

VANGL2 polyclonal antibody ( Cat # PAB7207 ) ( 0.3 µg/ml ) staining of mouse brain lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu, Ms E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Vang-like protein 2 (VANGL2) antibody

Western Blot: VANGL2 Antibody [NB100-59736] - NB100-59736 (0.3ug/ml) staining of Mouse Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat IgG Aff - Purified Bov, Hu, Ms, Ze E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Vang-like protein 2 (VANGL2) antibody

Immunohistochemistry-Paraffin: VANGL2 Antibody [NBP1-81428] Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in reaction center cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Vang-like protein 2 (VANGL2)

Vang-like protein 2 (VANGL2) Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

Vang-like protein 2 (VANGL2)

Vang-like protein 2 (VANGL2) Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

7 Item(s)

per page
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