VAV1 antibody

Principal name

VAV1 antibody

Alternative names for VAV1 antibody

VAV-1, Proto-oncogene vav

SwissProt ID

P15498 (Human), P27870 (Mouse), P54100 (Rat), Q08DN7 (Bovin)

Gene ID

7409 (VAV1), 22324 (Vav1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), African clawed frog

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of VAV1 antibody

Vav proteins belong to the guanidine nucleotide exchange factor family of proteins. These proteins couple receptors to Rho-GTPases. To date, three members of the Vav family have been identified in mammalian cells: Vav1, Vav2, and Vav3. Vav1 contains multiple protein binding motifs, indicating a role for Vav1 as an adaptor protein linking cell surface receptors to downstream signaling proteins. Vav1 is exclusively expressed in hematopoietic cells and plays a significant role in lymphocyte development and antigen receptor mediated activation of NFAT and NF B, and in more delayed responses such as the production of cytokines, including IL-2, IL-3, IFN- and TNF- . Vav1 is also reported to activate JNK, p21-activated kinase (PAK) and PLC , implicating its critical role in calcium mobilization, and cytoskeletal rearrangement. Activation of several cell surface receptors including integrins, immune response receptors, or growth factor receptors leads to phosphorylation of Vav1 on tyrosine residues including tyrosine 160.

General readings

Bustelo X R., et al. (1992) Nature. 356:68-71. Katzav S., et al. (1989) EMBO J. 8:2283-2290.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

VAV1 antibody

Sample(30 ug of whole cell lysate). A:MOLT4. B:Raji . 7.5% SDS PAGE. TA308739 diluted at 1:500 Rabbit IgG Aff - Purified Hu, Ms P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

VAV1 antibody

Western blot analysis of extracts from Jurkat cells, using VAV1 (Ab-174) Antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

VAV1 antibody

Predicted band size: 98 kDa . Positive control: Jurkat cells untreated or treated with H2O2 lysate. Recommended dilution: 1/ 500-1000. (Gel: 8%SDS-PAGE Lane1: Jurkat cells untreated with H2O2 lysate Lane2: Jurkat cells treated with H2O2 lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

VAV1 antibody

Predicted band size: 98 kDa . Positive control: Jurkat cells lysate. Recommended dilution: 1/ 500-1000. (Gel: 8%SDS-PAGE Lysate: 30 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

VAV1 antibody

Western blot analysis of VAV1 phosphorylation expression in K562 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

VAV1 antibody

VAV1 Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

VAV1 pTyr174 antibody

Figure 1. Western blot analysis of the extracts from Jurkat cells using Vav (phospho-Tyr174) antibody AP02427PU. Rabbit Aff - Purified Hu WB
0.1 ml / €320.00
  Acris Antibodies GmbH

VAV1 pTyr174 antibody

Figure 1. Western blot analysis of the extracts from Jurkat cells using Vav (phospho-Tyr174) antibody AP02427PU. Rabbit Aff - Purified Hu WB
50 µl / €240.00
  Acris Antibodies GmbH

VAV1 antibody

Figure 1. Western blot analysis of the extracts from Jurkat cells using Vav antibody AP02686PU. Rabbit Aff - Purified Hu, Rt WB
0.1 ml / €270.00
  Acris Antibodies GmbH

VAV1 antibody

Figure 1. Western blot analysis of the extracts from Jurkat cells using Vav antibody AP02686PU. Rabbit Aff - Purified Hu, Rt WB
50 µl / €230.00
  Acris Antibodies GmbH

VAV1 pTyr160 antibody

Western blot analysis using Vav1 [pY160] antibody on K562 cell lysate. Antibody activity was blocked by incubation of primary antibody with no peptide (1), non-phosphorylated immunogen peptide (2), general phosphotyrosine containing peptide (3) and phosphorylated immunogen peptide (4). Rabbit IgG Aff - Purified Hu WB
10 Blots / €730.00
  Acris Antibodies GmbH

VAV1 antibody

Immunohistochemistry (IHC) analyzes of VAV1 antibody (Cat.-No.: AP06359PU-N) in paraffin-embedded human lung carcinoma breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

VAV1 antibody

Western blot analysis of VAV1 antibody (Cat.-No.: AP20693PU-N) in extracts from K562 cells treated with UV 15'. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €350.00
  Acris Antibodies GmbH

VAV1 pTyr174 antibody

Western blot (WB) analyzes of p-Vav1 antibody (Cat.-No.: AP20816PU-N) in extracts from Jurkat UV cells. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €350.00
  Acris Antibodies GmbH

VAV1 antibody

Immunofluorescence of monoclonal antibody to VAV1 on HeLa cell. [antibody concentration 10 ug/ml] Mouse IgG2b 9C1 Purified Hu E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

VAV1 antibody

VAV1 monoclonal antibody (M02), clone 1A6 Western Blot analysis of VAV1 expression in HL-60 ( Cat # L014V1 ). Mouse IgG2a 1A6 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

VAV1 antibody

VAV1 monoclonal antibody (M03), clone 2C11 Western Blot analysis of VAV1 expression in Jurkat ( Cat # L017V1 ). Mouse IgG2a 2C11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

VAV1 antibody

Immunofluorescence of monoclonal antibody to VAV1 on HeLa cell. [antibody concentration 10 ug/ml] Mouse IgG2a 3A11 Purified Hu E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

VAV1 pTyr174 antibody

Western blot analysis of extracts from RAW264.7 cells, using VAV1 (Phospho-Tyr174) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €205.00
  Assay Biotech

VAV1 pTyr174 antibody

Western blot analysis of extracts from RAW264.7 cells, using VAV1 (Phospho-Tyr174) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €310.00
  Assay Biotech

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