VAV1 antibody

Principal name

VAV1 antibody

Alternative names for VAV1 antibody

VAV-1, Proto-oncogene vav

SwissProt ID

P15498 (Human), P27870 (Mouse), P54100 (Rat), Q08DN7 (Bovin)

Gene ID

7409 (VAV1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), African clawed frog

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Paraffin Sections (P), Flow Cytometry (F)

Background of VAV1 antibody

Vav proteins are guanine nucleotide exchange factors for Rho family GTPases which activate pathways leading to Actin cytoskeletal rearrangements and transcriptional alterations. Vav proteins contain several protein binding domains which can link cell surface receptors to downstream signaling proteins. Vav3 is a Ros receptor protein tyrosine kinase (RPTK) interacting protein and has a broad tissue expression profile that is distinct from those of Vav and Vav2. Vav3 mediates RPTK signaling and regulates GTPase activity, its native and mutant forms are able to modulate cell morphology, and it has the potential to induce cell transformation. For example, Vav3 induces marked membrane ruffles and microspikes in NIH-3T3 cells. Vav works as a GDP/GTP exchange factor for Rac GTPases, thereby facilitating the transition of these proteins from the inactive (GDP-bound) into the active (GTP-bound) state. The stimulation of Vav exchange activity during cell signaling is mediated by tyrosine phosphorylation. The residue, Tyrosine 174, is phosphorylated following the stimulation of mitogenic and antigenic receptors. This phosphorylation event is conserved in Vav2 and Vav3, the other two members of the Vav family

General readings

Bustelo X R., et al. (1992) Nature. 356:68-71. Katzav S., et al. (1989) EMBO J. 8:2283-2290.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

VAV1 antibody

Sample(30 ug of whole cell lysate). A:MOLT4. B:Raji . 7.5% SDS PAGE. TA308739 diluted at 1:500 Rabbit IgG Aff - Purified Hu, Ms P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

VAV1 antibody

Western blot analysis of extracts from Jurkat cells, using VAV1 (Ab-174) Antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

VAV1 antibody

Immunofluorescence analysis of HeLa cells, using VAV1 antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, ICC/IF
0.1 ml / €325.00
  OriGene Technologies, Inc.

VAV1 antibody

Predicted band size: 98 kDa . Positive control: Jurkat cells lysate. Recommended dilution: 1/ 500-1000. (Gel: 8%SDS-PAGE Lysate: 30 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

VAV1 antibody

VAV1 Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

VAV1 pTyr174 antibody

Figure 1. Western blot analysis of the extracts from Jurkat cells using Vav (phospho-Tyr174) antibody AP02427PU. Rabbit Aff - Purified Hu WB
0.1 ml / €320.00
  Acris Antibodies GmbH

VAV1 pTyr174 antibody

Figure 1. Western blot analysis of the extracts from Jurkat cells using Vav (phospho-Tyr174) antibody AP02427PU. Rabbit Aff - Purified Hu WB
50 µl / €240.00
  Acris Antibodies GmbH

VAV1 antibody

Figure 1. Western blot analysis of the extracts from Jurkat cells using Vav antibody AP02686PU. Rabbit Aff - Purified Hu, Rt WB
0.1 ml / €270.00
  Acris Antibodies GmbH

VAV1 antibody

Figure 1. Western blot analysis of the extracts from Jurkat cells using Vav antibody AP02686PU. Rabbit Aff - Purified Hu, Rt WB
50 µl / €230.00
  Acris Antibodies GmbH

VAV1 pTyr160 antibody

Western blot analysis using Vav1 [pY160] antibody on K562 cell lysate. Antibody activity was blocked by incubation of primary antibody with no peptide (1), non-phosphorylated immunogen peptide (2), general phosphotyrosine containing peptide (3) and phosphorylated immunogen peptide (4). Rabbit IgG Aff - Purified Hu WB
10 Blots / €710.00
  Acris Antibodies GmbH

VAV1 antibody

Immunohistochemistry (IHC) analyzes of VAV1 antibody (Cat.-No.: AP06359PU-N) in paraffin-embedded human lung carcinoma breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

VAV1 antibody

Western blot analysis of VAV1 antibody (Cat.-No.: AP20693PU-N) in extracts from K562 cells treated with UV 15'. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €350.00
  Acris Antibodies GmbH

VAV1 pTyr174 antibody

Western blot (WB) analyzes of p-Vav1 antibody (Cat.-No.: AP20816PU-N) in extracts from Jurkat UV cells. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €350.00
  Acris Antibodies GmbH

VAV1 antibody

Immunofluorescence of monoclonal antibody to VAV1 on HeLa cell. [antibody concentration 10 ug/ml] Mouse IgG2b 9C1 Purified Hu E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

VAV1 antibody

VAV1 monoclonal antibody (M02), clone 1A6 Western Blot analysis of VAV1 expression in HL-60 ( Cat # L014V1 ). Mouse IgG2a 1A6 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

VAV1 antibody

VAV1 monoclonal antibody (M03), clone 2C11 Western Blot analysis of VAV1 expression in Jurkat ( Cat # L017V1 ). Mouse IgG2a 2C11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

VAV1 antibody

Immunofluorescence of monoclonal antibody to VAV1 on HeLa cell. [antibody concentration 10 ug/ml] Mouse IgG2a 3A11 Purified Hu E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

VAV1 pTyr174 antibody

Western blot analysis of extracts from RAW264.7 cells, using VAV1 (Phospho-Tyr174) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €205.00
  Assay Biotech

VAV1 pTyr174 antibody

Western blot analysis of extracts from RAW264.7 cells, using VAV1 (Phospho-Tyr174) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €310.00
  Assay Biotech

VAV1 antibody

Immunofluorescence analysis of HeLa cells, using VAV1 (Ab-160) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF
50 µg / €205.00
  Assay Biotech

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