VEGFD antibody

Principal name

VEGFD antibody

Alternative names for VEGFD antibody

FIGF, VEGF-D, FIGF, Vascular endothelial growth factor D, c-Fos-induced growth factor

SwissProt ID

O35251 (Rat), O43915 (Human), P97946 (Mouse)

Gene ID

2277 (FIGF), 14205 (Figf)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Rb (Rabbit), Bov (Bovine)

Available hosts

Rabbit, Mouse, Rat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), Frozen Sections (C), EPair for Elisa (EPair), Immunoprecipitation (IP)

Background of VEGFD antibody

Vascular Endothelial Growth Factor D (VEGFD), also known as c-fos-induced growth factor (FIGF), is a member of the VEGF family of growth factors. Vascular endothelial growth factors (VEGFs) are a family of closely related growth factors having a conserved pattern of eight cysteine residues and sharing common VEGF receptors. VEGFs stimulate endothelial cells, induce angiogenesis, promote cell migration, increase vascular permeability, and inhibit apoptosis. VEGFD is most closely related to VEGFC (23.3% amino acid sequence identity) and has a similar VEGF homology domain that spans the middle third of the precursor protein and the long N-terminal and C-terminal extensions. In adults, VEGFD is highly expressed in lung, heart, muscle, and small intestine. VEGFD expression in fibroblasts is induced by cell interaction mediated by cadherin 11. Recombinant human VEGFD is a ligand for the tyrosine kinases, VEGFR2 (Flk1) and VEGF receptor 3 (Flt4). Since VEGFR3 is strongly expressed in lymphatic endothelial cells, it is postulated that VEGFD is involved in the regulation of the growth and/or differentiation of lymphatic endothelium and thus, a mitogen for endothelial cells.

General readings

1 Orlandini, M., et al., J. Biol. Chem. 278(45):44650-44656 (2003).
2. McColl, B.K., et al., J. Exp. Med. 198(6):863-868 (2003).
3. Rissanen, T.T., et al., Circ. Res. 92(10):1098-1106 (2003).
4. Nakamura, Y., et al., Clin. Cancer Res. 9(2):716-721 (2003).
5. Yokoyama, Y., et al., Br. J. Cancer 88(2):237-244 (2003).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

VEGFD antibody

Western blot analysis of VEGFD using recombinant human VEGF-D (50 ng). Rabbit Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

VEGFD antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FIGF (RC206549, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FIGF. Mouse IgG1 OTI6C5 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

VEGFD antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FIGF (RC206549, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FIGF. Mouse IgG1 OTI3C3 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

VEGFD antibody

Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-FIGF mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA807516) Mouse IgG2a OTI1C7 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

VEGFD antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FIGF (RC206549, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FIGF.(1:2000) Mouse IgG1 OTI2A1 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

VEGFD antibody

Figure 1. Western blot uising anti-VEGF4 Mab (Cat. #AM11020PU-N) to detect VEGF4 in HDMEC cell lysate. Mouse IgG1 28AT743.288.48 Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

VEGFD (C-term) antibody

Formalin-fixed and paraffin-embedded human lung carcinoma reacted with VEGF4 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

VEGFD antibody

Immunohistochemistry (IHC) analyzes of VEGF-D antibody (Cat.-No.. AP20769PU-N) in paraffin-embedded human lung carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

VEGFD (101-115) antibody

Staining with VEGF-D Polyclonal Antibody Rabbit IgG Aff - Purified Hu WB
0.1 mg / €340.00
  Acris Antibodies GmbH

VEGFD antibody

VEGFD Rabbit Azide Free Hu, Ms, Rt E, WB
0.2 mg / €330.00
  Acris Antibodies GmbH

VEGFD antibody

VEGFD Rabbit Azide Free Hu, Ms, Rt E, WB
0.1 mg / €250.00
  Acris Antibodies GmbH

VEGFD antibody

VEGFD Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

VEGFD antibody

Western Blot analysis of FIGF expression in transfected 293T cell line (H00002277-T01) by FIGF MaxPab polyclonal antibody.

Lane 1: FIGF transfected lysate(38.94 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

VEGFD antibody

VEGFD Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

VEGFD antibody

Immunoprecipitation of FIGF transfected lysate using anti-FIGF MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with FIGF MaxPab mouse polyclonal antibody (B01) (H00002277-B01). Rabbit Serum Hu E(detection), IP
0.1 ml / €380.00
  Abnova Taiwan Corp.

VEGFD antibody

Western Blot analysis of FIGF expression in transfected 293T cell line (H00002277-T01) by FIGF MaxPab polyclonal antibody.

Lane 1: FIGF transfected lysate(40.40 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

VEGFD antibody

VEGFD Mouse IgG2 2E79 Hu C, WB
0.1 mg / €730.00
  Abnova Taiwan Corp.

VEGFD antibody

VEGFD Rabbit IgG Hu, Ms, Rt E, WB
0.2 mg / €640.00
  Abnova Taiwan Corp.

VEGFD antibody

VEGFD Rat IgG2 8C35 Ms C, WB
0.1 mg / €730.00
  Abnova Taiwan Corp.

VEGFD antibody

Formalin-fixed and paraffin-embedded human lung carcinoma reacted with FIGF polyclonal antibody ( Cat # PAB4879 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. Rabbit Hu E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

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