Versican core protein / VCAN antibody

Principal name

Versican core protein / VCAN antibody

Alternative names for Versican core protein / VCAN antibody

CSPG2, GHAP, PG-M, Large fibroblast proteoglycan, Chondroitin sulfate proteoglycan core protein 2, Glial hyaluronate-binding protein

SwissProt ID

P13611 (Human), P81282 (Bovin), Q62059 (Mouse), Q90953 (Chick), Q9ERB4 (Rat)

Gene ID

1462 (VCAN)

Available reactivities

Hu (Human), Ms (Mouse), Rb (Rabbit), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Immunoprecipitation (IP), Enzyme Immunoassay (E), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C)

Background of Versican core protein / VCAN antibody

Versican(VCAN),also known as CSPG2, is a large extracellular matrix proteoglycan that is present in a variety of human tissues. Versican is a large chondroitin sulfate proteoglycan with an apparent molecular mass of more than 1000kDa.The Versican gene is mapped on 5q14.2-q14.3. The human versican gene contains 15 exons spanning more than 90 kb. The distribution of versican by using affinity-purified polyclonal antibodies that recognize the core protein of the prominent versican splice variants V0 and V1. Versican staining was noted in the central and peripheral nervous system, in the basal layer of the epidermis, and on the luminal surface of some glandular epithelia. Biochemical purification of LLC-conditioned medium led to identification of the extracellular matrix proteoglycan versican, which is upregulated in many human tumors including lung cancer, as a macrophage activator that acts through TLR2 and its coreceptors TLR6 and CD14. By activating TLR2:TLR6 complexes and inducing TNF-alpha secretion by myeloid cells, versican strongly enhances LLC metastatic growth.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Versican core protein / VCAN antibody

Immunohistochemical staining of human oral mucosa shows distinct positivity in extracellular matrix. This validation was performed by Protein Atlas and the presentation of data is for informational purposes only. Rabbit IgG Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Versican core protein / VCAN antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using VCAN antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Versican core protein / VCAN (362-585) antibody

Versican core protein / VCAN Mouse IgG1 S351-23 Purified Ms, Rt ICC/IF, WB
0.1 mg / €380.00
  Acris Antibodies GmbH

Versican core protein / VCAN (GAG) antibody

Versican core protein / VCAN Rabbit IgG Purified Ms IP, WB
50 µg / €410.00
  Acris Antibodies GmbH

Versican core protein / VCAN antibody

Versican core protein / VCAN Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Versican core protein / VCAN antibody

Versican core protein / VCAN Rabbit Aff - Purified Hu E, P
50 µg / €205.00
  Assay Biotech

Versican core protein / VCAN antibody

Versican core protein / VCAN Rabbit Aff - Purified Hu E, P
0.1 mg / €310.00
  Assay Biotech

Versican core protein / VCAN antibody

Versican core protein / VCAN Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €290.00
  Boster Immunoleader

Versican core protein / VCAN antibody

Western Blot: Versican Antibody [16770002] - Samples:  Lane 1, Marker [kDa]: 220, 112, 84, 47, 32, 26, 16.8  Lane 2, RT-4  Lane 3, U-251MG sp  Lane 4, Placenta  Lane 5, Liver  Lane 6, Tonsil ,  Target weight [kDa]:  373, 265, 182, 74 (splice variants)   Validation score:  2   Validation description:  Supportive - Band of predicted size in kDa (+/-20%) with additional bands present. Rabbit Hu E, P, WB
50 µg / €390.00
  Novus Biologicals Inc.

Versican core protein / VCAN control peptide

Western Blot: Versican Peptide [NB100-74563PEP] - Figure 1 shows a Western blot of versican in human aorta samples using NB100-74563PEP
50 µg / €420.00
  Novus Biologicals Inc.

Versican core protein / VCAN antibody

Immunohistochemistry-Paraffin: Versican Antibody [NBP1-85432] - Immunohistochemistry-Paraffin: Versican Antibody [NBP1-85432] Immunohistochemical staining of human cerebral cortex shows distinct positivity in neuropil. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Versican core protein / VCAN

Versican core protein / VCAN Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

Versican core protein / VCAN

Versican core protein / VCAN Human
10 µg / €380.00
  Abnova Taiwan Corp.

13 Item(s)

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