VHLL antibody

Principal name

VHLL antibody

Alternative names for VHLL antibody

Von Hippel-Lindau-like protein,VHL-like protein, VLP

Gene ID

391104 (VHLL)

Available reactivities

Hu (Human)

Available hosts

Mouse, Rabbit

Available applications

Western blot / Immunoblot (WB)

Background of VHLL antibody

Von Hippel-Lindau (VHL) tumor suppressor protein is a component of an E3 ubiquitin ligase complex that selectively ubiquitites the alpha subunit of the hypoxia-inducible factor (HIF) transcription factor for proteasome-mediated degradation. Ictivation of VHL causes VHL disease and sporadic kidney cancer. This gene encodes a VHL homolog that lacks one of two key domains necessary for VHL function. This gene may contribute to the regulation of oxygen homeostasis and neovascularization during placenta development. This gene is intronless, and can also be interpreted as a retrotransposed pseudogene of the VHL locus located on chromosome 3. However, the protein is represented in this RefSeq due to evidence in PMID:14757845 that strongly suggests it is translated. The same publication also indicates that this protein binds HIF alpha but fails to recruit the E3 ubiquitin ligase complex, and it therefore functions as a domint-negative VHL protein and a protector of HIF alpha.

4 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

VHLL antibody

VHLL Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

VHLL antibody

VHLL Mouse Hu WB
50 µg / €370.00
  Abnova Taiwan Corp.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

VHLL (full length, N-term HIS tag)

VHLL Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.


Catalog No.    

VHLL overexpression lysate

VHLL overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

4 Item(s)

per page
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