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VLDL-R / VLDL receptor antibody

Principal name

VLDL-R / VLDL receptor antibody

Alternative names for VLDL-R / VLDL receptor antibody

VLDLR, VTG receptor, VTGR, Vitellogenin receptor

SwissProt ID

P35953 (Rabit), P98155 (Human), P98156 (Mouse), P98165 (Chick), P98166 (Rat)

Gene ID

7436 (VLDLR)

Ncbi ID

NP_001018066.1, 9606, NP_001018066

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine)

Available hosts

Mouse, Rabbit, Chicken

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Functional assay (FN), Flow Cytometry (F), Immunohistochemistry (IHC)

Background of VLDL-R / VLDL receptor antibody

Very low-density lipoprotein receptor (VLDL-R) belongs to the low density lipoprotein receptor family. VLDL-R binds particles containing apolipoprotein E (apoE) with high affinity. This includes VLDL, which after being bound by VLDL-R is then transported into the cell via endocytosis. It also binds to Reelin, stimulating Dab1 phosphorylation and the regulation of Tau phosphorylation. VLDL-R expression has been observed at high levels in adipose tissue, brain, heart, kidney, ovary, and skeletal muscle. It is not present in the liver. Defects involving deletion of the VLDL-R sequence are thought to be the cause of VLDLR-associated cerebellar hypoplasia (VLDLRCH also known as DES), a cerebellar disorder characterized by delayed ambulation, moderate to severe mental retardation, primarily truncal ataxia.

General readings

Ruiz, J., et al. (2005), J. Lipid Res., 46: 1721- 1731

Western Blot: VLDL Receptor Lysate [NBL1-17729] - Western Blot experiments. Left-Control; Right -Over-expression Lysate for VLDLR

NBL1-17729

MCF7 cells were subjected to SDS PAGE followed by western blot with 19493-1-AP(VLDLR antibody) at dilution of 1:300

19493-1-AP

Mouse ovary tissue were subjected to SDS PAGE followed by western blot with 19493-1-AP(VLDLR antibody) at dilution of 1:300

19493-1-AP

Immunocytochemistry: VLDL Receptor Antibody (6A6) [NBP1-78162] - VLDL Receptor antibody was tested in HeLa cells with FITC (green). Nuclei and actin were counterstained with Dapi (blue) and Phalloidin (red).

NBP1-78162

Western Blot: VLDL Receptor Antibody (6A6) [NBP1-78162] - Western blot analysis of VLDL Receptor expression in mouse kidney using NBP1-78162.

NBP1-78162

Immunohistochemistry: VLDL Receptor Antibody (6A6) [NBP1-78162] - Immunohistochemical analysis of VLDL Receptor in mouse kidney using NBP1-78162._x000d__x000d_

NBP1-78162

L1 rat heart lysate L2 rat kidney lysates probed with Anti VLDL Polyclonal Antibody, Unconjugated (bs-4228R) at 1:200 overnight at 4˚C. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:3000 for 90 min at 37˚C. Predicted band 96kD. Observed band size: 96kD

bs-4228R

Formalin-fixed and paraffin embedded mouse embryo labeled with Anti-VLDL Polyclonal Antibody, Unconjugated (bs-4228R) at 1:200 followed by conjugation to the secondary antibody and DAB staining

bs-4228R

Western Blotting Analysis:
Representative lot data.
Mouse fetal brain tissue lysate was probed with Anti-VLDL-R, clone 6A6 (1 µg/mL).
Proteins were visualized using a Goat Anti-Mouse IgG secondary antibody conjugated to HRP and chemiluminescence detection system.
Arrow indicates VLDL-R (~143 kDa).

AM50595PU-N

Primary Antibodies

Catalog No.	Host	Iso.	Clone	Pres.	React.	Applications
TA309928	VLDL-R / VLDL receptor antibody
	Mouse	IgG1	6A6	Purified	Bov, Hu, Ms, Rt	ICC/IF, WB	0.1 ml / €325.00
							OriGene Technologies, Inc.
+1 additional image
AM00969PU-N	VLDL-R / VLDL receptor antibody
	Mouse	IgG1	B047M	Purified	Hu	E, WB	0.2 mg / €370.00
							Acris Antibodies GmbH
AM00970PU-N	VLDL-R / VLDL receptor antibody
	Mouse	IgG1	B046M	Purified	Hu	E	0.2 mg / €340.00
							Acris Antibodies GmbH
AM00971PU-N	VLDL-R / VLDL receptor antibody
	Mouse	IgG1	B045M	Purified	Hu	E, WB	0.2 mg / €450.00
							Acris Antibodies GmbH
MAB4252	VLDL-R / VLDL receptor antibody
	Mouse	IgG1	B047M		Hu	E, WB	0.2 mg / €470.00
							Abnova Taiwan Corp.
MAB4253	VLDL-R / VLDL receptor antibody
	Mouse	IgG1	B045M		Hu	E, WB	0.2 mg / €560.00
							Abnova Taiwan Corp.
MAB4254	VLDL-R / VLDL receptor antibody
	Mouse	IgG1	B046M		Hu	E	0.2 mg / €390.00
							Abnova Taiwan Corp.
F-BML028	VLDL-R / VLDL receptor antibody
	Mouse	IgG2a	LR-LL8H6	Purified	Hu	F, IHC, WB	50 µg / €640.00
							Funakoshi Co., Ltd.
F-BML029	VLDL-R / VLDL receptor antibody
	Mouse	IgG2b	LR-LL12D10	Purified	Hu	F, IHC, WB	50 µg / €640.00
							Funakoshi Co., Ltd.
F-BML030	VLDL-R / VLDL receptor antibody
	Mouse	IgG2b	VR-VP1-5C3	Purified	Hu	F, IHC, WB	50 µg / €990.00
							Funakoshi Co., Ltd.
F-BML031	VLDL-R / VLDL receptor antibody
	Mouse	IgG1	VR-VL1A9	Purified	Hu	F, IHC, WB	50 µg / €990.00
							Funakoshi Co., Ltd.
F-BML032	VLDL-R / VLDL receptor antibody
	Mouse	IgG2b	VR-VL9E11	Purified	Hu	F, IHC, WB	50 µg / €990.00
							Funakoshi Co., Ltd.
NB110-68193	VLDL-R / VLDL receptor antibody
	Mouse		B047M	Purified	Hu	E, WB	0.1 mg / €320.00
							Novus Biologicals Inc.
NB110-68195	VLDL-R / VLDL receptor antibody
	Mouse		B045M	Purified	Hu	E, WB	0.1 mg / €340.00
							Novus Biologicals Inc.
NBP1-78162SS	VLDL-R / VLDL receptor antibody
	Mouse	IgG1	6A6	Purified	Bov, Hu, Ms, Rt	ICC/IF, P, WB	25 µl / €200.00
							Novus Biologicals Inc.

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