VPRBP antibody

Principal name

VPRBP antibody

Alternative names for VPRBP antibody

HIV-1 Vpr-binding protein, DCAF1, KIAA0800, RIP, Vpr-interacting protein, DDB1- and CUL4-associated factor 1

SwissProt ID

Q80TR8 (Mouse), Q9Y4B6 (Human)

Gene ID

9730 (VPRBP)

Available reactivities

Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P), Western blot / Immunoblot (WB)

Background of VPRBP antibody

P55 is an extensively palmitoylated erythrocyte membrane protein, and a member of the MAGUK family. P55 also resists salt extraction, resulting in a high affinity for the plasma membrane. P55 contains a PDZ/DHR domain, a conserved SH-3 domain that appears to suppress tyrosine kinase activity of various oncoproteins, a 39-amino acid motif that binds to cytoskeletal protein 4.1R, and a guanylate kinase-like domain. Interaction with glycophorin C (GPC) and 4.1R suggests that p55 may play a role in the dynamic regulation in the erythrocyte membrane. In addition, p55 gene expression in vivo may be associated with a CpG island. P55 is constitutively expressed in K562 erythroleukemia cells during erythropoiesis and undergoes a 2-fold amplification after induction.

3 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

VPRBP antibody

Western Blot: VprBP Antibody [NBP1-05952] - Western Blot and Immunoprecipitation: VprBP Antibody [NBP1-05952]- Whole cell lysate from HeLa (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 ug), and mouse NIH3T3 (M; 50 ug) cells. Antibodies: Affinity purified rabbit anti-VprBP antibody used for WB at 0.04 ug/ml (A) and 1 ug/ml (B) and used for IP at 3 ug/mg lysate. VprBP was also immunoprecipitated by rabbit anti-VPRBP antibody NBP1-05951, which recognizes a downstream epitope. Rabbit IgG Aff - Purified Hu, Ms IP, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

VPRBP antibody

Western Blot and Immunoprecipitation: VprBP Antibody [NBP1-05953] - Whole cell lysate from HeLa and 293T (T; 50 ug) cells. VprBP was also immunoprecipitated byanother rabbit anti-VPRBP antibody NBP1-05952. Rabbit IgG Aff - Purified Hu IP, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

VPRBP antibody

Immunohistochemistry-Paraffin: VprBP Antibody [NBP1-85284] Immunohistochemical staining of human urinary bladder shows moderate cytoplasmic positivity in urothelial cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

3 Item(s)

per page
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