VPS4B antibody

Principal name

VPS4B antibody

Alternative names for VPS4B antibody

VPS42, SKD1, Vacuolar protein sorting-associated protein 4B, Suppressor of K(+) transport growth defect 1

SwissProt ID

O75351 (Human), P46467 (Mouse)

Gene ID

9525 (VPS4B)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of VPS4B antibody

Vacuolar protein sorting-associated protein 4B (Vps4), or SKD1, is a ubiquitous AAA ATPase involved in endosomal vesicle trafficking. Trafficking of vesicles containing proteins such as receptors, from the endosome to the cytoplasm, is an important regulatory mechanism for cell-surface receptors and the signaling pathways that involve those receptors. Such endosomal vesicles are shuttled from the endosome to the cytoplasm by multivesicular bodies (MVB). MVBs are large multi-protein complexes that assemble and disassemble during this process. Previous studies have indicated that the yeast homologue of Vps4, Vps4p (60 % sequence identity to Vps4), interacts with endosomes via its N-terminal microtubule interacting and trafficking (MIT) domain, and also associates with a number of MVB proteins including Vps2p, Bro1p, Vps20p, Vta1p, and Did2p/Chm1p. Although the precise role of Vps4 is still unclear, previous studies have suggested that it interacts with the ESCRT-III complex involved in the sorting of MVBs and has been associated with virus-loaded vesicles such those in HIV-infected cells.

General readings

Scheuring S., et al. (2001) J Mol Biol. 312:469-480. Perez O D., et al. (2001) Immunity. 15:687-690

9 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

VPS4B antibody

VPS4B polyclonal antibody (A01), Lot # 051206JC01 Western Blot analysis of VPS4B expression in Y-79 ( Cat # L042V1 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

VPS4B (N-term) antibody

Human OVCAR-3; WB Suggested Anti-VPS4B Antibody. . Titration: 1.0 ug/ml. . Positive Control: OVCAR-3 Whole Cell. VPS4B is supported by BioGPS gene expression data to be expressed in OVCAR3.; VPS4B antibody - N-terminal region (ARP61680_P050) in Human OVCAR-3 cells using Western Blot Rabbit Aff - Purified Hu
50 µg / €350.00
  AVIVA Systems Biology

VPS4B antibody

Western Blot: VPS4B  Antibody [NBP1-19118]-Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Affinity purified rabbit anti-VPS4B antibody used for IP at 3 mcg/mg lysate. VPS4B was also immunoprecipitated by rabbit anti- VPS4B antibody NBP1-19119, which recognizes a downstream epitope Rabbit IgG Aff - Purified Hu IP
0.1 ml / €440.00
  Novus Biologicals Inc.

VPS4B antibody

Western Blot and Immunoprecipitation: VPS4B Antibody [NBP1-19119] - Whole cell lysate from HeLa and 293T cells. VPS4B was also immunoprecipitated by rabbit anti-VPS4B antibody NBP1-19118. Rabbit IgG Aff - Purified Hu IP, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

VPS4B

VPS4B Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

VPS4B (1-444, His-tag)

VPS4B Human Purified > 90 % by SDS - PAGE E. coli
0.25 mg / €940.00
  Acris Antibodies GmbH

VPS4B (1-444, His-tag)

VPS4B Human Purified > 90 % by SDS - PAGE E. coli
50 µg / €370.00
  Acris Antibodies GmbH

VPS4B

VPS4B Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

VPS4B

VPS4B Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

9 Item(s)

per page
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