VSIG4 antibody

Principal name

VSIG4 antibody

Alternative names for VSIG4 antibody

CRIg, Z39IG, UNQ317/PRO362, V-set and immunoglobulin domain-containing protein 4

SwissProt ID

Q9Y279 (Human)

Gene ID

11326 (VSIG4)

Available reactivities

Bov (Bovine), Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of VSIG4 antibody

T cell activation by APCs is positively and negatively regulated by members of the B7 family. We have identified a previously unknown function for B7 familyrelated protein V-set and Ig domaincontaining 4 (VSIG4). Administration to mice of soluble VSIG4-Ig fusion molecules reduced the induction of T cell responses in vivo and inhibited the production of Th celldependent IgG responses. Unlike that of B7 family members, surface expression of VSIG4 was restricted to resting tissue macrophages and absent upon activation by LPS or in autoimmune inflammatory foci. The specific expression of VSIG4 on resting macrophages in tissue suggests that this inhibitory ligand may be important for the maintenance of T cell unresponsiveness in healthy tissues.

General readings

Otsuki,T., (2005) DNA Res. 12 (2), 117-126

9 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

VSIG4 antibody

Human Jurkat; WB Suggested Anti-VSIG4 Antibody Titration: 5.0ug/ml. Positive Control: Jurkat cell lysate; VSIG4 antibody - N-terminal region (ARP41591_T100) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Bov, Hu, Ms, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

VSIG4 antibody

Western Blot: VSIG4 Antibody [NBP1-69631] - This Anti-VSIG4 antibody was used in Western Blot of Jurkat tissue lysate at a concentration of 5ug/ml. Rabbit Purified Hu WB
0.1 mg / €360.00
  Novus Biologicals Inc.

VSIG4 antibody

Immunohistochemistry-Paraffin: VSIG4 Antibody [NBP1-86843] - Immunohistochemical staining of human testis shows strong nuclear positivity in cells in seminiferus ducts. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

VSIG4 (transcript variant 1)

VSIG4 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

VSIG4 (transcript variant 2)

VSIG4 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €299.00
  OriGene Technologies, Inc.

VSIG4 (transcript variant 1)

VSIG4 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €139.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

VSIG4 overexpression lysate

VSIG4 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

VSIG4 overexpression lysate

VSIG4 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

VSIG4 overexpression lysate

VSIG4 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

9 Item(s)

per page
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