VSIG4 antibody
Principal name
VSIG4 antibody
Alternative names for VSIG4 antibody
CRIg, Z39IG, UNQ317/PRO362, V-set and immunoglobulin domain-containing protein 4
SwissProt ID
Q9Y279 (Human)
Gene ID
11326 (VSIG4)
Ncbi ID
NP_009199, 9606, NP_001171759, NP_001171759.1, NM_007268, NM_001100431, NP_001093901
Available reactivities
Available hosts
Available applications
Western blot / Immunoblot (WB), Paraffin Sections (P)
Background of VSIG4 antibody
T cell activation by APCs is positively and negatively regulated by members of the B7 family. We have identified a previously unknown function for B7 familyrelated protein V-set and Ig domaincontaining 4 (VSIG4). Administration to mice of soluble VSIG4-Ig fusion molecules reduced the induction of T cell responses in vivo and inhibited the production of Th celldependent IgG responses. Unlike that of B7 family members, surface expression of VSIG4 was restricted to resting tissue macrophages and absent upon activation by LPS or in autoimmune inflammatory foci. The specific expression of VSIG4 on resting macrophages in tissue suggests that this inhibitory ligand may be important for the maintenance of T cell unresponsiveness in healthy tissues.
General readings
Otsuki,T., (2005) DNA Res. 12 (2), 117-126
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| ARP41591_T100 | VSIG4 antibody |
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 |
Rabbit | Aff - Purified | Bov, Hu, Ms, Rt | WB |
0.1 mg /
€310.00
|
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| AVIVA Systems Biology | |||||||
| NBP1-69631 | VSIG4 antibody |
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![Western Blot: VSIG4 Antibody [NBP1-69631] - This Anti-VSIG4 antibody was used in Western Blot of Jurkat tissue lysate at a concentration of 5ug/ml.](https://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/VSIG4 Antibody-Western Blot-NBP1-69631-img0001.jpg) |
Rabbit | Purified | Hu | WB |
0.1 mg /
€360.00
|
||
| Novus Biologicals Inc. | |||||||
| NBP1-86843 | VSIG4 antibody |
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![Immunohistochemistry-Paraffin: VSIG4 Antibody [NBP1-86843] - Immunohistochemical staining of human testis shows strong nuclear positivity in cells in seminiferus ducts.](https://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/VSIG4 Antibody-Immunohistochemistry-Paraffin-NBP1-86843-0005.jpg) |
Rabbit | IgG | Aff - Purified | Hu | P, WB |
0.1 ml /
€500.00
|
|
| Novus Biologicals Inc. | |||||||
 +1 additional image |
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Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP303751 | VSIG4 (transcript variant 1) |
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 |
Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
Regular Price: 20 µg / €680.00 Special Price: 20 µg / €398.00 |
|
| OriGene Technologies, Inc. | |||||
|
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| TP720454 | VSIG4 (transcript variant 2) |
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 |
Human | > 95 % Preparation: . Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
10 µg /
€299.00
|
|
| OriGene Technologies, Inc. | |||||
| TP720837 | VSIG4 (transcript variant 1) |
||||
 |
Human | > 95 % Preparation: . Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
10 µg /
€139.00
|
|
| OriGene Technologies, Inc. | |||||
Lysates (Overexpressed)
| Catalog No. | ||
|---|---|---|
| LY416087 | VSIG4 overexpression lysate |
|
|
0.1 mg /
€280.00
|
|
| OriGene Technologies, Inc. | ||
| LY420270 | VSIG4 overexpression lysate |
|
|
0.1 mg /
€280.00
|
|
| OriGene Technologies, Inc. | ||
| LY426114 | VSIG4 overexpression lysate |
|
|
0.1 mg /
€280.00
|
|
| OriGene Technologies, Inc. |
