VSX2 / CHX10 antibody

Principal name

VSX2 / CHX10 antibody

Alternative names for VSX2 / CHX10 antibody

HOX10, Visual system homeobox 2, Homeobox protein CHX10, Ceh-10 homeodomain-containing homolog

SwissProt ID

P58304 (Human), Q61412 (Mouse), Q9IAL1 (Chick)

Gene ID

338917 (VSX2), 12677 (Vsx2)

Available reactivities

Can (Canine), Hu (Human), Ms (Mouse), Bov (Bovine), Rt (Rat)

Available hosts

Rabbit, Sheep, Mouse

Available applications

Western blot / Immunoblot (WB), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), ELISA (detection) (E(detection)), Enzyme Immunoassay (E)

Background of VSX2 / CHX10 antibody

CHX10 is a 40kDa homeodomain protein of the paired-like class that is essential for development of the mammalian eye. Mutations in CHX10 cause microphthalmia, a cause of congenital blindness in humans, and the ocular retardation (or) phenotype in mice. In the developing mouse retina CHX10 is expressed in retinal progenitors, while in the mature retina, CHX10 expression becomes restricted to bipolar neurons. Concurrent with these expression patterns, the CHX10-/- (or) retina is thin due to a defect in proliferation of retinal progenitors, and lacks bipolar neurons. CHX10 is also expressed in the developing brainstem, thalamus, and spinal cord.

General readings

General / background references:Chen CM & Cepko CL Expression of Chx10 and Chx10-1 in the developing chicken retina. Mech Dev 90:293-7 (2000). PubMed PMID: 10640715
Ferda Percin E et al. Human microphthalmia associated with mutations in the retinal homeobox gene CHX10. Nat Genet 25:397-401 (2000). PubMed PMID: 10932181
Liu IS et al. Developmental expression of a novel murine homeobox gene (Chx10): evidence for roles in determination of the neuroretina and inner nuclear layer. Neuron 13:377-93 (1994). PubMed PMID: 7914735

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

VSX2 / CHX10 (C-term) antibody

Western blot analysis using anti-Chk10 (CT) antibody at 1 µg/ml on rat liver (A), retina tissue lysate (B), mouse liver (C) and retina (D) tissue lysate. Sheep IgG Purified Ms, Rt C, WB
0.25 mg / €360.00
  Acris Antibodies GmbH

VSX2 / CHX10 (N-term) antibody

Western blot analysis using anti-Chk10 (NT) antibody at 1 µg/ml on rat liver (A), retina tissue lysate (B), mouse liver (C) and retina (D) tissue lysate. Sheep IgG Purified Ms, Rt C, WB
0.25 mg / €360.00
  Acris Antibodies GmbH

VSX2 / CHX10 antibody

WB Suggested Anti-CHX10 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:12500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

VSX2 / CHX10 (C-term) antibody

VSX2 Antibody (C-term) (AP54526PU-N) western blot analysis in 293 cell line lysates (35 µg/lane). This demonstrates the VSX2 antibody detected the VSX2 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

VSX2 / CHX10 antibody

VSX2 / CHX10 Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

VSX2 / CHX10 antibody

Western blot analysis using VSX2 polyclonal antibody at 1 µg/ml on rat liver (lane 1), retina tissue lysate (lane 2), mouse liver (lane 3) and retina (lane 4) tissue lysate. Sheep Purified Hu, Ms, Rt C, WB
0.25 mg / €400.00
  Abnova Taiwan Corp.

VSX2 / CHX10 antibody

Western blot analysis using VSX2 polyclonal antibody at 1 µg/ml on rat liver (lane 1), retina tissue lysate (lane 2), mouse liver (lane 3) and retina (lane 4) tissue lysate. Sheep Purified Hu, Ms, Rt C, WB
0.25 mg / €400.00
  Abnova Taiwan Corp.

VSX2 / CHX10 antibody

Human Jurkat; WB Suggested Anti-CHX10 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:12500. Positive Control: Jurkat cell lysate; CHX10 antibody - C-terminal region (ARP31974_P050) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Can, Hu, Ms WB
50 µg / €350.00
  AVIVA Systems Biology

VSX2 / CHX10 antibody

VSX2 / CHX10 Sheep IgG Purified Bov, Hu, Ms, Rt WB
0.25 mg / €530.00
  Novus Biologicals Inc.

VSX2 / CHX10 antibody

Immunohistochemistry-Paraffin: CHX10 Antibody [NBP1-84476] - Immunohistochemical staining of human oral mucosa shows moderate nuclear(nucleolar) positivity in squamous epithelial cells. Rabbit IgG Aff - Purified Hu ICC/IF, P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

VSX2 / CHX10

VSX2 / CHX10 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

VSX2 / CHX10

VSX2 / CHX10 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

VSX2 / CHX10

VSX2 / CHX10 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

CHX10 293T Cell Transient Overexpression Lysate(Denatured)

CHX10 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

Lysates (Overexpressed)

Catalog No.    

VSX2 overexpression lysate

VSX2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

15 Item(s)

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