Whirlin antibody

Principal name

Whirlin antibody

Alternative names for Whirlin antibody

WHRN, DFNB31, KIAA1526, Autosomal recessive deafness type 31 protein

SwissProt ID

Q80VW5 (Mouse), Q810W9 (Rat), Q9P202 (Human)

Gene ID

25861 (DFNB31), 73750 (Whrn)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C)

Background of Whirlin antibody

DFNB31 (deafness autosomal recessive 31) is a PDZ scaffold protein which is necessary for elongation and maintenance of stereocilia in the inner and outer hair cells in the organ of Corti in the inner ear. It is also expressed in retinal photoreceptor cells. Mutations in this gene, also known as Whirlin, are associated with non syndromic sensorineural deafness autosomal recessive type 31 and retinitis pigmentosa. DFNB31 interacts with a calmodulin dependent serine kinase, CASK, and may be involved in the formation of scaffolding protein complexes that facilitate synaptic transmission in the central nervous system.

General readings

Letra, A., et al. Am. J. Med. Genet. A 152A (7), 1701-1710 (2010).
Secolin, R., et al. Psychiatr. Genet. 20(3):126-129 (2010).
Aller, E., et al. Mol. Vis. 16, 495-500 (2010).
Toiyama, Y., et al. Int. J. Oncol. 35(4):709-715 (2009).
Gosens, I., et al. Hum. Mol. Genet. 16(16):1993-2003 (2007).

12 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Whirlin (Center) antibody

Formalin fixed and paraffin embedded stomach tissue reacted with Whirlin Antibody Cat.-No AP51246PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Whirlin antibody

Whirlin Rabbit Serum Hu C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

Whirlin antibody

Whirlin Rabbit Serum Ms C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

Whirlin antibody

Whirlin Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Whirlin antibody

Detection limit for recombinant GST tagged DFNB31 is approximately 0.03ng/ml as a capture antibody. Mouse IgG2b 1D9 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Whirlin antibody

Whirlin Mouse IgG1 2D12 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Whirlin antibody

Whirlin Rabbit IgG Aff - Purified Hu, Ms WB
50 µg / €680.00
  Funakoshi Co., Ltd.

Whirlin antibody

Whirlin Rabbit Serum Hu, Ms, Rt E, P, WB
0.2 ml / €400.00
  Novus Biologicals Inc.

Whirlin antibody

Immunohistochemistry-Paraffin: DFNB31 Antibody [NBP1-85611] - Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells of tubules. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Whirlin antibody

Immunohistochemistry-Paraffin: DFNB31 Antibody [NBP1-85612] Immunohistochemical staining of human duodenum shows strong granular positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Whirlin

Whirlin Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Whirlin

Whirlin Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

12 Item(s)

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