WIPI-2 antibody

Principal name

WIPI-2 antibody

Alternative names for WIPI-2 antibody

WIPI2, CGI-50, WD repeat domain phosphoinositide-interacting protein 2, WIPI49-like protein 2

SwissProt ID

Q6AY57 (Rat), Q7ZWU5 (Xenla), Q80W47 (Mouse), Q9Y4P8 (Human)

Gene ID

26100 (WIPI2), 6261006 (IPR001669)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of WIPI-2 antibody

WIPI2 Antibody: WD repeat proteins play a role in many essential biologic functions, regulating the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. WIPI2, also known as ATG18B or ATG21, is a human homolog to yeast ATG18 and contains three WD repeats and has a 7-bladed propeller structure with a conserved motif that facilitates its interaction with other proteins. It is recruited to early autophagosomal structures along with Atg16L and ULK1 and is required for the formation of LC3-positive autophagosomes. Along with the highly related WIPI1, WIPI2 is found at the plasma membrane in addition to autophagosomal membranes.

General readings

Polson HE, de Lartique J, Rigden DJ, et al. Mammalian ATG18 (WIPI2) localizes to moegasome-anchored phagophores and positively regulates LC3 lipidation. Autophagy 2010; 6:506-22.

11 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

WIPI-2 (N-term) antibody

Western blot analysis of WIPI2 in human testis tissue lysate with WIPI2 antibody at 1 ug/mL Rabbit IgG Aff - Purified Hu, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

WIPI-2 antibody

Host: Rabbit; Target Name: WIPI2; Sample Tissue: OVCAR-3 Whole Cell lysates; Antibody Dilution: 1.0ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

WIPI-2 (C-term) antibody

Western blot analysis of WIPI2 Antibody (C-term) (AP54567PU-N) in mouse brain tissue lysates (35 µg/lane). WIPI2 (arrow) was detected using the purified Pab. Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

WIPI-2 (N-term) Control Peptide

WIPI-2
50 µg / €160.00
  Acris Antibodies GmbH

WIPI-2 antibody

Immunohistochemistry-Paraffin: WIPI2 Antibody [NBP1-88879] - Immunohistochemical staining of human skeletal muscle shows strong cytoplasmic positivity in selected fibers. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

WIPI-2 antibody

Immunohistochemistry-Paraffin: WIPI2 Antibody [NBP1-88880] - Immunohistochemical staining of human testis shows distinct cytoplasmic positivity in seminiferus duct cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

WIPI-2

WIPI-2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

WIPI-2

WIPI-2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

WIPI2 overexpression lysate

WIPI2 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

WIPI2 overexpression lysate

WIPI2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

WIPI2 overexpression lysate

WIPI2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

11 Item(s)

per page
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