WISP1 antibody

Principal name

WISP1 antibody

Alternative names for WISP1 antibody

CCN4, WNT1-inducible-signaling pathway protein 1, CCN family member 4, Wnt-1-induced secreted protein

SwissProt ID

O54775 (Mouse), O95388 (Human), Q99PP0 (Rat)

Gene ID

8840 (WISP1), 22402 (Wisp1), 65154

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Goat, Mouse

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C)

Background of WISP1 antibody

This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. It is expressed at a high level in fibroblast cells, and overexpressed in colon tumors. The encoded protein binds to decorin and biglycan, two members of a family of small leucine-rich proteoglycans present in the extracellular matrix of connective tissue, and possibly prevents the inhibitory activity of decorin and biglycan in tumor cell proliferation. It also attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase. It is 83% identical to the mouse protein at the amino acid level. Multiple alternatively spliced transcript variants have been identified.

General readings

Major MB, Camp ND, Berndt JD, Yi X, Goldenberg SJ, Hubbert C, Biechele TL, Gingras AC, Zheng N, Maccoss MJ, Angers S, Moon RT.
Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling.
Science. 2007 May 18;316(5827):1043-6.
PMID: 17510365

Items 1 to 20 of 21 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

WISP1 (C-term) antibody

  Goat Polyclonal Antibody against WISP1  
TA302635 (0.1µg/ml) staining of HEK293 cell lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

WISP1 antibody

  CCN4 / WISP1 Rabbit Polyclonal (aa185-200) Antibody  
Anti-WISP1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. Rabbit Purified Hu E, P
50 µg / €400.00
  OriGene Technologies, Inc.

WISP1 antibody

  Rabbit Polyclonal Anti-WISP1 Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using (WISP1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

WISP1 antibody

  Rabbit Polyclonal WISP1 Antibody  
WISP1 Rabbit IgG Purified Hu
50 µg / €325.00
  OriGene Technologies, Inc.

WISP1 (Center) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

Wisp1 - mouse gene knockout kit via CRISPR

Wisp1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Wisp1 - mouse gene knockout kit via CRISPR

Wisp1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Wisp1 - mouse gene knockout kit via CRISPR

Wisp1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Wisp1 - mouse gene knockout kit via CRISPR

Wisp1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

WISP1 (transcript variant 1)

  Recombinant protein of human WNT1 inducible signaling pathway protein 1 (WISP1), transcript variant 1  
WISP1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

WISP1 (transcript variant 1)

  Purified recombinant protein of Human WNT1 inducible signaling pathway protein 1 (WISP1), transcript variant 1.  
WISP1 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli

Regular Price: 20 µg / €199.00

Special Price: 20 µg / €139.00

  OriGene Technologies, Inc.

ELISA Kits

Catalog No.    

Human WISP1/CCN4 ELISA Kit

Human WISP1/CCN4 ELISA Kit  
1 kit / €389.00
  OriGene Technologies, Inc.

Mouse WISP1/CCN4 ELISA Kit

Mouse WISP1/CCN4 ELISA Kit  
1 kit / €389.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

WISP1 overexpression lysate

WISP1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

WISP1 overexpression lysate

WISP1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, WISP1 (mGFP-tagged) - Human WNT1 inducible signaling pathway protein 1 (WISP1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, WISP1 (mGFP-tagged) - Human WNT1 inducible signaling pathway protein 1 (WISP1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, WISP1 (Myc-DDK tagged) - Human WNT1 inducible signaling pathway protein 1 (WISP1), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, WISP1 (Myc-DDK tagged) - Human WNT1 inducible signaling pathway protein 1 (WISP1), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Wisp1 (GFP-tagged) - Mouse WNT1 inducible signaling pathway protein 1 (Wisp1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Wisp1 (GFP-tagged) - Mouse WNT1 inducible signaling pathway protein 1 (Wisp1), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Wisp1 (Myc-DDK-tagged) - Mouse WNT1 inducible signaling pathway protein 1 (Wisp1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Wisp1 (Myc-DDK-tagged) - Mouse WNT1 inducible signaling pathway protein 1 (Wisp1), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Wisp1 (GFP-tagged ORF) - Rat WNT1 inducible signaling pathway protein 1 (Wisp1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Wisp1 (GFP-tagged ORF) - Rat WNT1 inducible signaling pathway protein 1 (Wisp1), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Items 1 to 20 of 21 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn