WISP1 antibody

Principal name

WISP1 antibody

Alternative names for WISP1 antibody

CCN4, WNT1-inducible-signaling pathway protein 1, CCN family member 4, Wnt-1-induced secreted protein

SwissProt ID

O54775 (Mouse), O95388 (Human), Q99PP0 (Rat)

Gene ID

8840 (WISP1), 22402 (Wisp1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Goat, Rabbit, Mouse, Rat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Dot blot (Dot), Frozen Sections (C), Immunoprecipitation (IP)

Background of WISP1 antibody

This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. It is expressed at a high level in fibroblast cells, and overexpressed in colon tumors. The encoded protein binds to decorin and biglycan, two members of a family of small leucine-rich proteoglycans present in the extracellular matrix of connective tissue, and possibly prevents the inhibitory activity of decorin and biglycan in tumor cell proliferation. It also attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase. It is 83% identical to the mouse protein at the amino acid level. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq]. Transcript Variant: This variant (2) lacks an exon within the coding region but the reading frame remains, as compared to variant 1. Isoform 2 encoded by this variant thus lacks a von Willbrand type C module that is thought to participate in protein complex formation. This variant is overexpressed in scirrhous carcinomas. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Major MB, Camp ND, Berndt JD, Yi X, Goldenberg SJ, Hubbert C, Biechele TL, Gingras AC, Zheng N, Maccoss MJ, Angers S, Moon RT.
Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling.
Science. 2007 May 18;316(5827):1043-6.
PMID: 17510365

Items 1 to 20 of 24 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

WISP1 (C-term) antibody

TA302635 (0.1µg/ml) staining of HEK293 cell lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

WISP1 antibody

Anti-WISP1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. Rabbit Purified Hu E, P
50 µg / €345.00
  OriGene Technologies, Inc.

WISP1 antibody

WISP1 Rabbit IgG Purified Hu
50 µg / €325.00
  OriGene Technologies, Inc.

WISP1 (Center) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

WISP1 antibody

Immunoperoxidase of purified MaxPab antibody to WISP1 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml] Mouse Purified Hu E(detection), ICC/IF, P, WB
50 µg / €370.00
  Abnova Taiwan Corp.

WISP1 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with WISP1 polyclonal antibody ( Cat # PAB4835 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma. Rabbit Hu E, P
0.4 ml / €390.00
  Abnova Taiwan Corp.

WISP1 antibody

293 overexpressing WISP1 with C-terminal tag ( DYKDDDDK ) and probed with WISP1 polyclonal antibody ( Cat # PAB7404 ) in the left panel. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

WISP1 antibody

WISP1 Rabbit IgG Aff - Purified Hu, Ms, Rt C, ICC/IF, P, WB
0.1 mg / €290.00
  Boster Immunoleader

WISP1 antibody

WISP1 Rabbit Hu E, P, WB
50 µg / €440.00
  Novus Biologicals Inc.

WISP1 antibody

Western Blot: WISP1 Antibody[NB100-77339]-HEK293 overexpressing WISP1 (RC214390) with C-terminal tag (DYKDDDDK) and probed with anti-DYKDDDDK in the left panel and with EB08178 in the right panel (mock transfection in first and last lanes), tested by Origene. Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

WISP1 antibody

Western Blot: WISP1 Antibody [NBP1-31230] - Western blot analysis of WISP1 Antibody on: A:A431 10% SDS PAGE diluted at 1:1000 Rabbit IgG Hu Dot, ICC/IF, P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

WISP1 antibody

Immunohistochemistry-Paraffin: WISP1 Antibody [NBP1-86570] Immunohistochemical staining of human small intestine shows cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

WISP1 (transcript variant 1)

WISP1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

WISP1 (transcript variant 1)

WISP1 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli

Regular Price: 20 µg / €199.00

Special Price: 20 µg / €139.00

  OriGene Technologies, Inc.

WISP1

WISP1 Human > 98 % pure by SDS-PAGE gel and HPLC analyses E. coli
5 µg / €140.00
  Acris Antibodies GmbH

WISP1

WISP1 Human > 98 % pure by SDS-PAGE gel and HPLC analyses E. coli
20 µg / €230.00
  Acris Antibodies GmbH

WISP1

WISP1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

WISP1

WISP1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

WISP1

WISP1 Human
20 µg / €290.00
  Abnova Taiwan Corp.

ELISA Kits

Catalog No.    

Human WISP1 ELISA Kit

Representative Standard Curve  
96 Tests / €450.00
  Cohesion Biosciences Ltd.

Items 1 to 20 of 24 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn