WNK4 antibody
Principal name
WNK4 antibody
Alternative names for WNK4 antibody
Serine/threonine-protein kinase WNK4, PRKWNK4, Protein kinase with no lysine 4, Protein kinase lysine-deficient 4
Gene ID
65266 (WNK4)
Ncbi ID
Available reactivities
Available hosts
Available applications
Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)
Background of WNK4 antibody
Regulates the activity of the thiazide-sensitive Na-Cl cotransporter, SLC12A3, by phosphorylation which appears to prevent membrane trafficking of SLC12A3. Also inhibits the renal K(+)channel, KCNJ1, via a kinase-independent mechanism by which it induces clearance of the protein from the cell surface by clathrin-dependent endocytosis. WNK4 appears to act as a molecular switch that can vary the balance between NaCl reabsorption and K(+)secretion to maintain integrated homeostasis.
Western Blot: WNK4 Antibody [NB600-284] - Detection of WNK4 in mouse kidney lysate.
Western Blot: WNK4 Antibody [GTX30604] - Detection of WNK4 in mouse kidney lysate.
Western blot analysis of WNK4 in mouse kidney lysate with WNK4 polyclonal antibody ( Cat# PAB11980 ).
Immunohistochemistry-Paraffin: WNK4 Antibody [NBP1-92597] Immunohistochemical staining of human kidney shows strong cytoplasmic and nuclear positivity in cells in tubules.
Mouse lung tissue were subjected to SDS PAGE followed by western blot with 22326-1-AP( WNK4 Antibody) at dilution of 1:300
Mouse liver tissue were subjected to SDS PAGE followed by western blot with 22326-1-AP( WNK4 Antibody) at dilution of 1:600
Mouse colon tissue were subjected to SDS PAGE followed by western blot with 22326-1-AP( WNK4 Antibody) at dilution of 1:600
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA309931 | WNK4 antibody |
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 |
Rabbit | Purified | Hu, Ms, Rt | WB |
0.1 ml /
€325.00
|
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| OriGene Technologies, Inc. | |||||||
| H00065266-M02 | WNK4 antibody |
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 |
Mouse | IgG1 | 1E6 | Purified | Hu | E, WB |
0.1 mg /
€370.00
|
| Abnova Taiwan Corp. | |||||||
| PAB11980 | WNK4 antibody |
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 |
Rabbit | Hu, Ms, Rt | WB |
0.1 ml /
€470.00
|
|||
| Abnova Taiwan Corp. | |||||||
| NB600-284B | WNK4 antibody |
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|
Rabbit | Biotin | Hu, Ms, Rt | WB |
0.1 ml /
€360.00
|
||
| Novus Biologicals Inc. | |||||||
| NB600-284G | WNK4 antibody |
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|
Rabbit | DyLight488 | Hu, Ms, Rt | WB |
0.1 ml /
€390.00
|
||
| Novus Biologicals Inc. | |||||||
| NB600-284H | WNK4 antibody |
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|
Rabbit | HRP | Hu, Ms, Rt | WB |
0.1 ml /
€390.00
|
||
| Novus Biologicals Inc. | |||||||
| NB600-284SS | WNK4 antibody |
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|
Rabbit | Hu, Ms, Rt | WB |
25 µl /
€170.00
|
|||
| Novus Biologicals Inc. | |||||||
| NBP1-92597 | WNK4 antibody |
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![Immunohistochemistry-Paraffin: WNK4 Antibody [NBP1-92597] Immunohistochemical staining of human kidney shows strong cytoplasmic and nuclear positivity in cells in tubules.](https://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/WNK4 Antibody-Immunohistochemistry-Paraffin-NBP1-92597-0005.jpg) |
Rabbit | IgG | Aff - Purified | Hu | P |
0.1 ml /
€500.00
|
|
| Novus Biologicals Inc. | |||||||
Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP323269 | WNK4 |
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 |
Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€680.00
|
|
| OriGene Technologies, Inc. | |||||
| H00065266-Q01-10 | WNK4 |
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|
Human | Purified | 12.5% SDS-PAGE Stained with Coomassie Blue. |
10 µg /
€380.00
|
|
| Abnova Taiwan Corp. | |||||
| H00065266-Q01-25 | WNK4 |
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|
Human | Purified | 12.5% SDS-PAGE Stained with Coomassie Blue. |
25 µg /
€510.00
|
|
| Abnova Taiwan Corp. | |||||
| P5665 | WNK4 |
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|
Human |
5 µg /
€610.00
|
|||
| Abnova Taiwan Corp. | |||||
Lysates (Overexpressed)
| Catalog No. | ||
|---|---|---|
| LY410153 | WNK4 overexpression lysate |
|
|
0.1 mg /
€480.00
|
|
| OriGene Technologies, Inc. |
