WNT7A antibody

Principal name

WNT7A antibody

Alternative names for WNT7A antibody

Wnt-7a

SwissProt ID

O00755 (Human), P24383 (Mouse), P31288 (Xenla)

Gene ID

7476 (WNT7A), 22421 (Wnt7a)

Available reactivities

Can (Canine), Hu (Human), Mky (Monkey), Ms (Mouse), Rt (Rat), Bov (Bovine), Chimp (Chimpanzee), Eq (Equine), Hst (Hamster), Por (Porcine), Rb (Rabbit), Gorilla, Chk (Chicken), GP (Guinea Pig), Xen (Xenopus)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB)

Background of WNT7A antibody

Wnt-7a belongs to the Wnt family of signaling proteins that play a key role in maintaining the integrity of embryonic and adult tissues. It is expressed in placenta, kidney, testis, uterus, fetal lung and fetal and adult brain. Most Wnt proteins can signal though a mechanism called the canonical Wnt pathway, in which Wnt proteins bind to and activate seven-pass transmembrane receptors of the Frizzled family ultimately leading to the disruption of beta-Catenein degradation. Intracellular accumulation of Beta-Catenin increases translocation of the protein into the nucleus where it binds to TCF/LEF transcription factors and induces the expression of numerous genes. Increased Wnt/beta-Catenein signaling is associated with tumorigenesis in a diverse set of Human cancers. However, Wnt-7a/Frizzled-9 signaling has been shown to act as a tumor suppressor in non-small cell lung cancers.

General readings

Bui T.D., Lako M.. et al. (1997). Gene 189:25-29

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

WNT7A antibody

  WNT7A Rabbit Polyclonal (Internal) Antibody  
Anti-WNT7A antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Purified Bov, Can, Chimp, Eq, Gorilla, Hst, Hu, Mky, Ms, Por, Rb, Rt
50 µg / €400.00
  OriGene Technologies, Inc.

WNT7A antibody

  WNT7A Rabbit Polyclonal (Internal) Antibody  
Anti-WNT7A antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Purified Bov, Can, Chimp, Chk, Eq, Gorilla, GP, Hst, Hu, Mky, Ms, Por, Rb, Rt, Xen
50 µg / €400.00
  OriGene Technologies, Inc.

WNT7A antibody

  Rabbit Polyclonal WNT7A Antibody  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY WNT7A (RC202417, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-WNT7A. Rabbit IgG Purified Can, Hu, Mky, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

WNT7A - human gene knockout kit via CRISPR

WNT7A - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

WNT7A - human gene knockout kit via CRISPR

WNT7A - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

WNT7A - human gene knockout kit via CRISPR

WNT7A - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

WNT7A - human gene knockout kit via CRISPR

WNT7A - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Wnt7a - mouse gene knockout kit via CRISPR

Wnt7a - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Wnt7a - mouse gene knockout kit via CRISPR

Wnt7a - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Wnt7a - mouse gene knockout kit via CRISPR

Wnt7a - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Wnt7a - mouse gene knockout kit via CRISPR

Wnt7a - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

WNT7A

  Purified recombinant protein of Human wingless-type MMTV integration site family, member 7A (WNT7A).  
WNT7A Human > 80 %
Preparation: .
Purity Detail: >80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 15 µg / €399.00

Special Price: 15 µg / €239.00

  OriGene Technologies, Inc.

WNT7A

WNT7A Human > 80 % by SDS-PAGE gel and HPLC analyses HEK293 cells
15 µg / €230.00
  Acris Antibodies GmbH

WNT7A

WNT7A Human > 80 % by SDS-PAGE gel and HPLC analyses HEK293 cells
3 µg / €140.00
  Acris Antibodies GmbH

WNT7A (32-349, His-tag)

WNT7A Human Purified > 85 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

WNT7A (32-349, His-tag)

WNT7A Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

WNT7A overexpression lysate

WNT7A overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, WNT7A (mGFP-tagged) - Human wingless-type MMTV integration site family, member 7A (WNT7A), 200 uL, >10^7 TU/mL

Lenti ORF particles, WNT7A (mGFP-tagged) - Human wingless-type MMTV integration site family, member 7A (WNT7A), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, WNT7A (Myc-DDK tagged) - Human wingless-type MMTV integration site family, member 7A (WNT7A) , 200 uL, >10^7 TU/mL

Lenti ORF particles, WNT7A (Myc-DDK tagged) - Human wingless-type MMTV integration site family, member 7A (WNT7A) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Wnt7a (GFP-tagged) - Mouse wingless-related MMTV integration site 7A (Wnt7a), 200 uL, >10^7 TU/mL

Lenti ORF particles, Wnt7a (GFP-tagged) - Mouse wingless-related MMTV integration site 7A (Wnt7a), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

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