WRN antibody

Principal name

WRN antibody

Alternative names for WRN antibody

RECQ3, RECQL2, DNA helicase, RecQ-like type 3, RecQ3, RecQ protein-like 2, Werner syndrome ATP-dependent helicase, Exonuclease WRN

SwissProt ID

O09053 (Mouse), O93530 (Xenla), Q14191 (Human)

Gene ID

7486 (WRN)

Available reactivities

Hu (Human), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)

Background of WRN antibody

The Werner’s syndrome helicase (RecQ-like type 3; RecQ3; Exonuclease WRN) is a ubiquitously expressed nuclear protein belonging to the RecQ family. It functions as a helicase and exonuclease enzyme, and plays a crucial role in the formation of DNA replication centers. This protein is also involved in DNA repair and recombination, and may be involved in transcriptional events mediated by RNA polymerase II. It is regulated by phosphorylation and is targeted by the DNA-dependent protein kinase enzyme. Disrupted expression of the gene encoding the Werner’s syndrome helicase protein often results in the production of truncated Werner’s syndrome helicase proteins. Over 50 gene mutations may contribute to this effect—and lead to the development of Werner syndrome, a condition characterized by accelerated aging and early onset of age-related conditions such as cancer, atherosclerosis, and osteoporosis.

17 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

WRN (Center) antibody

WRN Antibody (Center T802) (Cat. #TA324470) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the WRN antibody detected the WRN protein (arrow). Rabbit Ig Aff - Purified Hu F, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

WRN antibody

ELISA: WRN Antibody Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

WRN antibody

WRN Mouse IgG1 N260/17 Supernatant Hu, Rt WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

WRN antibody

WRN Mouse IgG1 N260/17 Purified Hu, Rt WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

WRN antibody

WRN Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

WRN antibody

WRN monoclonal antibody (M06), clone 2F7. Western Blot analysis of WRN expression in Jurkat(Cat # L017V1 ). Mouse IgG1 2F7 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

WRN antibody

Immunofluorescence of monoclonal antibody to WRN on HeLa cell. [antibody concentration 10 ug/ml] Mouse IgG2a 3C11 Purified Hu E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

WRN (223-237) antibody

The BCN antibody recognizes WRN, and its decrease in the presence of siRNA. Whole cell extracts (30 μg) from HEK-293 cells with or without siRNA where fractionated in a 6% SDS-PAGE, transferred to nitrocellulose membrane, and probed with the anti-WRN BCN antibody diluted 1:100. Peroxidase-conjugated anti-rabbit antibodies followed by ECL were then used. Rabbit IgG Aff - Purified Hu WB
50 µl / €280.00
  Antibody BCN

WRN pSer1141 antibody

Western blot analysis of extracts from K562 cells treated with etoposide 25uM 24h, using Werner Syndrome Helicase (Phospho-Ser1141) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €205.00
  Assay Biotech

WRN pSer1141 antibody

Western blot analysis of extracts from K562 cells treated with etoposide 25uM 24h, using Werner Syndrome Helicase (Phospho-Ser1141) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €310.00
  Assay Biotech

WRN antibody

ELISA: WRN Antibody [25480002] Rabbit Hu E, P, WB
50 µg / €440.00
  Novus Biologicals Inc.

WRN antibody

Western Blot and  Immunoprecipitation: WRN Antibody [NB100-471] - Detection of human WRN on HeLa whole cell lysate using NB100-471. WRN was immunoprecipitated with NB100-471 or rabbit anti-WRN antibody NB100-472. Rabbit Aff - Purified Hu IP, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

WRN antibody

Immunohistochemistry-Paraffin: WRN Antibody [NB100-472] - FFPE section of human seminoma.  Affinity purified rabbit anti-WRN used at a dilution of 1:250. Detection: DAB staining using Immunohistochemistry Accessory Kit Rabbit Aff - Purified Hu IP, P, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

WRN antibody

Western blot: WRN Antibody [NBP1-31895]- (30 ug of whole cell lysate) A: A431 (GTX27909) 5% SDS PAGE Rabbit IgG Hu ICC/IF, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

WRN antibody

Immunohistochemistry-Paraffin: WRN Antibody [NBP1-87143] - Immunohistochemical staining of human placenta shows strong nuclear positivity in trophoblastic cells and moderate nuclear and cytoplasmic staining in decidual cells. Rabbit IgG Aff - Purified Hu ICC/IF, P
0.1 ml / €500.00
  Novus Biologicals Inc.

WRN antibody

Western Blot: WRN Antibody (EPR6392) [NBP1-95901] (A) Molt-4, (B) K562, and (C) A431 cell lysates using anti-WRN. Rabbit EPR6392 Purified Hu WB
0.1 ml / €420.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

WRN

WRN Human
2 µg / €300.00
  Abnova Taiwan Corp.

17 Item(s)

per page
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