WT1 / Wilms tumor protein antibody
Principal name
WT1 / Wilms tumor protein antibody
Alternative names for WT1 / Wilms tumor protein antibody
WT33
Gene ID
7490 (WT1)
Ncbi ID
NP_000526, NP_000369, 9606, NP_077742, AAH32861.1, NP_000369.3, NM_000378, NM_024426, NM_024425, NM_001198552, NM_024424
Available reactivities
Available hosts
Available applications
Paraffin Sections (P), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection)), Frozen Sections (C)
Selected product citations ‐ of AP15857PU-M
1. Yates LL, Papakrivopoulou J, Long DA, Goggolidou P, Connolly JO, Woolf AS, et al. The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation. Hum Mol Genet. 2010 Dec 1;19(23):4663-76. doi: 10.1093/hmg/ddq397. Epub 2010 Sep 14. PubMed PMID: 20843830.
2. Vasilopoulou, E;Kolatsi-Joannou, M;Lindenmeyer, MT;White, KE;Robson, MG;Cohen, CD;Sebire, NJ;Riley, PR;Winyard, PJ;Long, DA;2016Loss of endogenous thymosin β4 accelerates glomerular disease. Kidney Int. PubMed PMID: 27575556
Background of WT1 / Wilms tumor protein antibody
WT1 is a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm\'s tumors. Multiple transcript variants, resulting from alternative splicing at two coding exons, have been well characterized. There is also evidence for the use of non-AUG (CUG) translation initiation site upstream of, and in-frame with the first AUG, leading to additional isoforms.This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm\'s tumors. Multiple transcript variants, resulting from alternative splicing at two coding exons, have been well characterized. There is also evidence for the use of non-AUG (CUG) translation initiation site upstream of, and in-frame with the first AUG, leading to additional isoforms. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated.
General readings
Ruteshouser,E.C., (2008) Genes Chromosomes Cancer 47 (6), 461-470






















Primary Antibodies
Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
---|---|---|---|---|---|---|---|
AP54572PU-N | WT1 / Wilms tumor protein (Center) antibody |
||||||
![]() |
Rabbit | Ig | Aff - Purified | Hu | ICC/IF, P, WB |
0.4 ml /
€415.00
|
|
OriGene Technologies GmbH | |||||||
![]() |