XAF1 antibody

Principal name

XAF1 antibody

Alternative names for XAF1 antibody

XIAPAF1, BIRC4BP, XIAP-associated factor 1, BIRC4-binding protein

SwissProt ID

Q58DH1 (Bovin), Q5NBU8 (Mouse), Q6GPH4 (Human)

Gene ID

54739 (XAF1), 327959 (Xaf1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C)

Background of XAF1 antibody

XAF-1 binds to XIAP, an inhibitor of caspases-3, -7, and -9, and triggers its relocation from the cytosol to the nucleus (1,2). Overexpression of XAF-1 results in the neutralization of XIAP\'s ability to inhibit cell death (1). XAF-1 is normally expressed in all adult and fetal tissues but was found to be present in very low levels in a variety of cancer cell lines (3). In contrast, XIAP levels have been shown to be high in a majority of cell lines. Low XAF-1 and high basal expression of XIAP may therefore play a critical role in maintaining survival of cancer cell lines (2,3). Both IFN-alpha2 and IFN-beta can induce XAF-1 mRNA in all cells examined but induction of XAF-1 protein (as observed by immunoblot analysis) was seen only in cell lines sensitive to the apoptotic effects of IFNs (4).

General readings

Liston P., et al (2001). Nat. Cell Biol. 3:128-133Leaman D.W., et al (2002). J. Biol. Chem. 277:28504-28511

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

XAF1 antibody

Western blot analysis of XAF-1 in human spleen lysate with XAF-1 antibody at 0.5 (lane A), 1 (lane B), and 2 (lane C) ug/ml, respectively. Rabbit IgG Aff - Purified Hu, Ms E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

XAF1 (Center) antibody

Western blot analysis of XAF-1 in human spleen lysate with XAF-1 antibody (IN) at 1 (lane A), 2 (lane B), and 4 (lane C) µg/ml, respectively. Rabbit IgG Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

XAF1 antibody

WB Suggested Anti-XAF1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Human Small Intestine Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

XAF1 antibody

WB Suggested Anti-XAF1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Hela cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

XAF1 antibody

Spleen: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu P, WB
50 µg / €470.00
  Acris Antibodies GmbH

XAF1 antibody

Figure 1. Staining XAF1 in Prostate by Immunohistochemistry using Formalin-Fixed Paraffin-Embedded (FFPE) tissue. Rabbit Aff - Purified Hu, Ms P, WB
50 µg / €470.00
  Acris Antibodies GmbH

XAF1 (C-term) antibody

XAF1 Polyclonal Antibody Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

XAF1 Control Peptide

XAF1
50 µg / €160.00
  Acris Antibodies GmbH

XAF1 Control Peptide

XAF1
50 µg / €160.00
  Acris Antibodies GmbH

XAF1 antibody

Immunofluorescence of purified MaxPab antibody to BIRC4BP on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

XAF1 antibody

XAF1 MaxPab rabbit polyclonal antibody. Western Blot analysis of XAF1 expression in mouse liver. Rabbit Purified Hu, Ms E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

XAF1 antibody

XAF1 monoclonal antibody (M05), clone 3E5. Western Blot analysis of XAF1 expression in Hela NE(Cat # L013V3 ). Mouse IgG2a 3E5 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

XAF1 antibody

Western blot analysis of XAF1 in human liver lysates using XAF1 polyclonal antibody ( Cat # PAB0190 ) at 1 µg/ml. Rabbit Hu P, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

XAF1 antibody

Western blot analysis of XAF1 expression in Jurkat cell lysate. Rabbit Hu WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

XAF1 antibody

Immunohistochemical staining of XAF1 on formalin fixed, paraffin embedded human epidermic carcinoma with XAF1 polyclonal antibody ( Cat # PAB12307 ). Rabbit Hu, Ms, Rt P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

XAF1 antibody

Immunohistochemical staining of human spleen tissue using XAF1 polyclonal antibody ( Cat # PAB13116 ) at 2 µg/ml. Rabbit Hu, Ms P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

XAF1 antibody

Western blot analysis of XAF1 in human spleen lysate with XAF1 polyclonal antibody ( Cat # PAB13125 ) at 1 ( lane A ), 2 ( lane B ), and 4 ( lane C ) µg/ml, respectively. Rabbit Hu WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

XAF1 antibody

Human Jurkat; Host:Rabbit. Target Name:XAF1. Sample Tissue:Human Jurkat. Antibody Dilution: 1.0ug/ml. XAF1 is supported by BioGPS gene expression data to be expressed in Jurkat.; XAF1 antibody - middle region (ARP56969_P050) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

XAF1 antibody

Human Small Intestine; WB Suggested Anti-XAF1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Human Small Intestine; XAF1 antibody - middle region (ARP56970_P050) in Human Small Intestine cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

XAF1 antibody

XAF1 Rabbit IgG Aff - Purified Hu P, WB
0.1 mg / €290.00
  Boster Immunoleader

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