XPA / XPAC antibody

Principal name

XPA / XPAC antibody

Alternative names for XPA / XPAC antibody

DNA repair protein complementing XP-A cells, Xeroderma pigmentosum group A-complementing protein

SwissProt ID

P23025 (Human), P27089 (Chick), Q64267 (Mouse)

Gene ID

7507 (XPA)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of XPA / XPAC antibody

Xeroderma pigmentosum (XP) is an autosomal recessive disorder characterized by a genetic predisposition to sunlight-induced skin cancer due to deficiencies in the DNA repair enzymes. The most frequent mutations are found in the XP genes of group A through G and group V, which encode nucleotide excision repair proteins. The XPA gene encodes a 31 kDa zinc metalloprotein that preferentially binds to DNA damaged by UV radiation and chemical carcinogens and is required for the incision step during nucleotide excision repair. The XPB and XPD genes encode DNA helicases involved in several DNA metabolic pathways, including DNA repair and transcription, and the XPG gene product is an endonuclease that cuts on the 3' side of a DNA lesion during nucleotide excision repair. Molecular defects in the XP variant (XPV) group maintain normal excision repair, yet they result in a substantial reduction in the ability to synthesize intact daughter DNA strands during DNA replication following DNA damage.

General readings

Pan Y.R., et al. (2009) Cell Cycle 8:655-664James, et al. (2005) Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders.

Items 1 to 20 of 33 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

XPA / XPAC antibody

Western blot analysis of extracts from COLO205 cells, using XPA antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

XPA / XPAC antibody

Predicted band size: 31 kDa . Positive control: HEK-293 cell lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 40 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

XPA / XPAC antibody

Western blot analysis of extracts of various cell lines , using XPA antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

XPA / XPAC antibody

Western blot analysis on COLO205 cell lysate using XPA Antibody Rabbit IgG Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

XPA / XPAC antibody

ELISA: XPA Antibody Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

XPA / XPAC antibody

The lysate of SW480 (30ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human XPA antibody(1:500 ~ 1:2000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG3 AT37C5 Purified Hu E, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

XPA / XPAC antibody

The lysate of SW480 (30ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human XPA antibody(1:500 ~ 1:2000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG3 AT37C5 Purified Hu E, WB
50 µl / €220.00
  Acris Antibodies GmbH

XPA / XPAC antibody

Western blot (WB) analysis of XPA antibody (Cat.-No.: AP06479PU-N) in extracts from COLO205 cells. Rabbit Aff - Purified Hu, Ms P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

XPA / XPAC (C-term) antibody

Western blot analysis of XPA Antibody (C-term) (AP18245PU-N) in NCI-H460 cell line lysates (35ug/lane). XPA (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

XPA / XPAC antibody

XPA / XPAC Rabbit Serum Hu WB
0.1 ml / €340.00
  Acris Antibodies GmbH

XPA / XPAC antibody

Immunofluorescence of purified MaxPab antibody to XPA on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

XPA / XPAC antibody

Western Blot analysis of XPA expression in transfected 293T cell line (H00007507-T02) by XPA MaxPab polyclonal antibody.

Lane 1: XPA transfected lysate(31.40 KDa).
Lane 2: Non-transfected lysate. Rabbit Serum Hu, Ms E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

XPA / XPAC antibody

XPA MaxPab rabbit polyclonal antibody. Western Blot analysis of XPA expression in mouse kidney. Rabbit Purified Hu, Ms E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

XPA / XPAC antibody

XPA / XPAC Mouse IgG2a 2E4 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

XPA / XPAC antibody

Formalin-fixed, paraffin-embedded human tonsil stained with XPA monoclonal antibody, clone 12F5 ( Cat # MAB3418 ). Mouse IgG2a 12F5 Hu IP, P, WB
0.1 mg / €820.00
  Abnova Taiwan Corp.

XPA / XPAC antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using XPA Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P, WB
50 µg / €205.00
  Assay Biotech

XPA / XPAC antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using XPA Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P, WB
0.1 mg / €310.00
  Assay Biotech

XPA / XPAC antibody

Immunohistochemical analysis of XPA staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Can, Hu, Ms P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

XPA / XPAC antibody

Immunohistochemical analysis of XPA staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Can, Hu, Ms P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

XPA / XPAC antibody

Immunohistochemical analysis of XPA staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Can, Hu, Ms P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

Items 1 to 20 of 33 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn