XPA / XPAC antibody

Principal name

XPA / XPAC antibody

Alternative names for XPA / XPAC antibody

DNA repair protein complementing XP-A cells, Xeroderma pigmentosum group A-complementing protein

SwissProt ID

P23025 (Human), P27089 (Chick), Q64267 (Mouse)

Gene ID

7507 (XPA), 22590 (Xpa)

Available reactivities

Hu (Human), Ms (Mouse), Can (Canine), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E)

Background of XPA / XPAC antibody

Xeroderma pigmentosum (XP) is an autosomal recessive disorder characterized by a genetic predisposition to sunlight-induced skin cancer due to deficiencies in the DNA repair enzymes. The most frequent mutations are found in the XP genes of group A through G and group V, which encode nucleotide excision repair proteins. The XPA gene encodes a 31 kDa zinc metalloprotein that preferentially binds to DNA damaged by UV radiation and chemical carcinogens and is required for the incision step during nucleotide excision repair. The XPB and XPD genes encode DNA helicases involved in several DNA metabolic pathways, including DNA repair and transcription, and the XPG gene product is an endonuclease that cuts on the 3' side of a DNA lesion during nucleotide excision repair. Molecular defects in the XP variant (XPV) group maintain normal excision repair, yet they result in a substantial reduction in the ability to synthesize intact daughter DNA strands during DNA replication following DNA damage.

General readings

Pan Y.R., et al. (2009) Cell Cycle 8:655-664James, et al. (2005) Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders.

18 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

XPA / XPAC antibody

  Rabbit polyclonal anti-XPA antibody  
Western blot analysis of extracts from COLO205 cells, using XPA antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

XPA / XPAC antibody

  Anti-XPA Rabbit Polyclonal Antibody  
Predicted band size: 31 kDa . Positive control: HEK-293 cell lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 40 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

XPA / XPAC antibody

  XPA Rabbit Polyclonal Antibody  
Western blot analysis of extracts of various cell lines , using XPA antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €335.00
  OriGene Technologies, Inc.

XPA / XPAC antibody

  Rabbit Polyclonal Anti-XPA Antibody  
Western blot analysis on COLO205 cell lysate using XPA Antibody Rabbit IgG Purified Hu, Ms WB
0.1 mg / €335.00
  OriGene Technologies, Inc.

XPA / XPAC antibody

  Rabbit Polyclonal XPA Antibody  
ELISA: XPA Antibody Rabbit IgG Purified Hu E
0.1 mg / €409.00
  OriGene Technologies, Inc.

XPA / XPAC antibody

Western blot (WB) analysis of XPA antibody (Cat.-No.: AP06479PU-N) in extracts from COLO205 cells. Rabbit Aff - Purified Hu, Ms P, WB
0.1 mg / €350.00
  OriGene Technologies GmbH

XPA / XPAC (C-term) antibody

Western blot analysis of XPA Antibody (C-term) (AP18245PU-N) in NCI-H460 cell line lysates (35ug/lane). XPA (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €370.00
  OriGene Technologies GmbH

XPA / XPAC antibody

XPA / XPAC Rabbit Serum Hu WB
0.1 ml / €350.00
  OriGene Technologies GmbH

XPA / XPAC antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using XPA Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P, WB
50 µg / €230.00
  Assay Biotech

XPA / XPAC antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using XPA Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P, WB
0.1 mg / €330.00
  Assay Biotech

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

XPA / XPAC (1-273, His-tag)

XPA / XPAC Human Purified > 85 % by SDS - PAGE E. coli
0.5 mg / €730.00
  OriGene Technologies GmbH

XPA / XPAC (1-273, His-tag)

XPA / XPAC Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / €300.00
  OriGene Technologies GmbH

Lysates

Catalog No.    

XPA overexpression lysate

XPA overexpression lysate  
0.1 mg / €295.00
  OriGene Technologies, Inc.

Lysates (Knockout)

Catalog No.    

XPA-knockout Cell lysate

XPA-knockout Cell lysate  
0.1 mg / €495.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Xpa (GFP-tagged) - Mouse xeroderma pigmentosum, complementation group A (cDNA clone MGC:36016 IMAGE:4489063), 200 uL, >10^7 TU/mL

Lenti ORF particles, Xpa (GFP-tagged) - Mouse xeroderma pigmentosum, complementation group A (cDNA clone MGC:36016 IMAGE:4489063), 200 uL, >10^7 TU/mL  
200 µl / €1,206.00
  OriGene Technologies, Inc.

Lenti ORF particles, Xpa (GFP-tagged) - Mouse xeroderma pigmentosum, complementation group A (Xpa), 200 uL, >10^7 TU/mL

Lenti ORF particles, Xpa (GFP-tagged) - Mouse xeroderma pigmentosum, complementation group A (Xpa), 200 uL, >10^7 TU/mL  
200 µl / €907.00
  OriGene Technologies, Inc.

Lenti ORF particles, Xpa (Myc-DDK-tagged) - Mouse xeroderma pigmentosum, complementation group A (cDNA clone MGC:36016 IMAGE:4489063), 200 uL, >10^7 TU/mL

Lenti ORF particles, Xpa (Myc-DDK-tagged) - Mouse xeroderma pigmentosum, complementation group A (cDNA clone MGC:36016 IMAGE:4489063), 200 uL, >10^7 TU/mL  
200 µl / €1,082.00
  OriGene Technologies, Inc.

Lenti ORF particles, Xpa (Myc-DDK-tagged) - Mouse xeroderma pigmentosum, complementation group A (Xpa), 200 uL, >10^7 TU/mL

Lenti ORF particles, Xpa (Myc-DDK-tagged) - Mouse xeroderma pigmentosum, complementation group A (Xpa), 200 uL, >10^7 TU/mL  
200 µl / €804.00
  OriGene Technologies, Inc.

18 Item(s)

per page
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