XRCC2 antibody

Principal name

XRCC2 antibody

Alternative names for XRCC2 antibody

DNA repair protein XRCC2, X-ray repair cross-complementing protein 2

SwissProt ID

O43543 (Human), Q9CX47 (Mouse)

Gene ID

7516 (XRCC2)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat), Mky (Monkey), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), ELISA (detection) (E(detection))

Background of XRCC2 antibody

The x-ray repair cross-complementing (XRCC) proteins are responsible for efficiently repairing and maintaining genetic stability following DNA base damage. These genes share sequence similarity with the yeast DNA repair protein Rad5. XRCC1 is a protein that facilitates the DNA base excision repair pathway by interacting with DNA ligase III and DNA polymerase to repair DNA single-strand breaks. XRCC2 and XRCC3 are both involved in maintaining chromosome stability during cell division. XRCC2 is required for efficient repair of DNA double-strand breaks by homologous recombination between sister chromatids, and XRCC3 interacts directly with Rad51 to cooperate with Rad51 during recombinational repair. XRCC4 is an accessory factor of DNA ligase IV that preferentially binds DNA with nicks or broken ends. XRCC4 binds to DNA ligase IV and enhances its joining activity, and it is also involved in V(D)J recombination. Any defect in one of the known components of the DNA repair/V(D)J recombination machinery (Ku-70, Ku-80, DNA-PKCS, XRCC4 and DNA ligase IV) leads to abortion of the V(D)J rearrangement process and early block in both T and B cell maturation.

General readings

General / background references:Johnson RD et al. Mammalian XRCC2 promotes the repair of DNA double-strand breaks by homologous recombination. Nature 401:397-9 (1999). PubMed PMID: 10517641
Tambini CE et al. The XRCC2 DNA repair gene: identification of a positional candidate. Genomics 41:84-92 (1997). PubMed PMID: 9126486

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

XRCC2 antibody

AP15859PU-N XRCC2 antibody staining of Human Testis. Rabbit Purified Hu P, WB
0.5 ml / €360.00
  Acris Antibodies GmbH

XRCC2 antibody

AP15859PU-N XRCC2 antibody staining of Human Testis. Rabbit Purified Hu P, WB
1 ml / €440.00
  Acris Antibodies GmbH

XRCC2 antibody

AP15859PU-N XRCC2 antibody staining of Human Testis. Rabbit Purified Hu P, WB
0.1 ml / €180.00
  Acris Antibodies GmbH

XRCC2 antibody

Sample. A: 30ug of Raji whole cell lysate . 12% SDS PAGE. TA308789 diluted at 1:1000 Rabbit IgG Aff - Purified Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

XRCC2 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using XRCC2 antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

XRCC2 antibody

Western blot analysis of extracts of various cell lines, using XRCC2 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

XRCC2 antibody

WB Suggested Anti-XRCC2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Human Muscle Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

XRCC2 antibody

Immunohistochemistry (IHC) analyzes of XRCC2 antibody (Cat.-No.: AP06481PU-N) in paraffin-embedded human lung carcinoma tissue. Rabbit Aff - Purified Hu P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

XRCC2 antibody

Western Blot analysis of XRCC2 expression in transfected 293T cell line (H00007516-T01) by XRCC2 MaxPab polyclonal antibody.

Lane 1: XRCC2 transfected lysate(30.8 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

XRCC2 antibody

Western Blot analysis of XRCC2 expression in transfected 293T cell line (H00007516-T01) by XRCC2 MaxPab polyclonal antibody.

Lane 1: XRCC2 transfected lysate(32.00 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

XRCC2 antibody

Detection limit for recombinant GST tagged XRCC2 is approximately 0.3ng/ml as a capture antibody. Mouse IgG2a 2H4 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

XRCC2 antibody

Immunohistochemical staining of XRCC2 on formalin fixed, paraffin embedded human testis with XRCC2 polyclonal antibody. Rabbit Hu P, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

XRCC2 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using XRCC2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, P
50 µg / €205.00
  Assay Biotech

XRCC2 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using XRCC2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, P
0.1 mg / €310.00
  Assay Biotech

XRCC2 antibody

Human Muscle; WB Suggested Anti-XRCC2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Human Muscle; XRCC2 antibody - middle region (ARP58558_P050) in Human Muscle cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

XRCC2 antibody

Immunohistochemical analysis of XRCC2 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Mky P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

XRCC2 antibody

Immunohistochemical analysis of XRCC2 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Mky P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

XRCC2 antibody

Immunohistochemical analysis of XRCC2 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Mky P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

XRCC2 antibody

Immunohistochemistry-Paraffin: XRCC2 Antibody [NB100-92126] - Paraffin-embedded human lung carcinoma tissue. Rabbit IgG Aff - Purified Hu P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

XRCC2 antibody

Immunohistochemistry: XRCC2 Antibody [NB120-2367] - Formalin fixed paraffin embedded human testis stained with XRCC2 antibody. Rabbit IgG Hu P, WB
0.5 ml / €420.00
  Novus Biologicals Inc.

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