XRCC4 antibody

Principal name

XRCC4 antibody

Alternative names for XRCC4 antibody

DNA repair protein XRCC4, X-ray repair cross-complementing protein 4

SwissProt ID

Q13426 (Human), Q924T3 (Mouse)

Gene ID

7518 (XRCC4), 108138 (Xrcc4)

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), EPair for Elisa (EPair), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Immunoprecipitation (IP)

Background of XRCC4 antibody

The x-ray repair cross-complementing (XRCC) proteins are responsible for efficiently repairing and maintaining genetic stability following DNA base damage. These genes share sequence similarity with the yeast DNA repair protein Rad51. XRCC1 is a 70 kDa protein that facilitates the DNA base excision repair pathway by interacting with DNA ligase III and DNA polymerase to repair DNA single-strand breaks. XRCC2 and XRCC3 are both involved in maintaining chromosome stability during cell division. XRCC2 is required for efficient repair of DNA double-strand breaks by homologous recombination between sister chromatids, and XRCC3 interacts directly with Rad51 to cooperate with Rad51 during recombinational repair. XRCC4 is an accessory factor of DNA ligase IV that preferentially binds DNA with nicks or broken ends. XRCC4 binds to DNA ligase IV and enhances its joining activity, and it is also involved in V(D)J recombination. Any defect in one of the known components of the DNA repair/V(D)J recombination machinery (Ku-70, Ku-80, DNA-PKCS, XRCC4 and DNA ligase IV) leads to abortion of the V(D)J rearrangement process and early block in both T and B cell maturation.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

XRCC4 antibody

  anti-XRCC4 mouse monoclonal antibody, clone OTI4H9 (formerly 4H9)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-XRCC4 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500650, Dilution 1:50) Mouse IgG1 OTI4H9 Purified Hu P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

XRCC4 antibody

  Rabbit Polyclonal antibody to XRCC4 (X-ray repair complementing defective repair in Chinese hamster cells 4)  
Sample (30 ug of whole cell lysate). A: Jurkat. B: K562. C: HL-60. 10% SDS PAGE. TA308834 diluted at 1:1000. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

XRCC4 antibody

  Rabbit polyclonal anti-XRCC4 antibody  
Western blot analysis of extracts from COLO205 cells, using XRCC4 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

XRCC4 antibody

  XRCC4 Rabbit Polyclonal Antibody  
Western blot analysis of extracts of various cell lines , using XRCC4 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

XRCC4 antibody

  Rabbit Polyclonal Anti-XRCC4 Antibody  
WB Suggested Anti-XRCC4 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:2500; Positive Control: Human Placenta Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Por, Rb WB
50 µg / €325.00
  OriGene Technologies, Inc.

XRCC4 antibody

  Rabbit Polyclonal Anti-XRCC4 Antibody  
Western blot analysis on COLO205 cell lysate using XRCC4 Antibody Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

XRCC4 antibody

  Rabbit Polyclonal XRCC4 Antibody  
ELISA: XRCC4 Antibody - Affinity Purified Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

XRCC4 antibody

Western blot(WB) analysis of XRCC4 antibody (Cat.-No.: AP06483PU-N) in extracts from COLO205 cells. Rabbit Aff - Purified Hu WB
0.1 mg / €350.00
  Acris Antibodies GmbH

XRCC4 antibody

Western blot analysis of extracts from COLO205 cells, using XRCC4 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €230.00
  Assay Biotech

XRCC4 antibody

Western blot analysis of extracts from COLO205 cells, using XRCC4 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

XRCC4 - human gene knockout kit via CRISPR

XRCC4 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

XRCC4 - human gene knockout kit via CRISPR

XRCC4 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

XRCC4 - human gene knockout kit via CRISPR

XRCC4 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

XRCC4 - human gene knockout kit via CRISPR

XRCC4 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Xrcc4 - mouse gene knockout kit via CRISPR

Xrcc4 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Xrcc4 - mouse gene knockout kit via CRISPR

Xrcc4 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Xrcc4 - mouse gene knockout kit via CRISPR

Xrcc4 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Xrcc4 - mouse gene knockout kit via CRISPR

Xrcc4 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

XRCC4 (transcript variant 3)

  Recombinant protein of human X-ray repair complementing defective repair in Chinese hamster cells 4 (XRCC4), transcript variant 3  
XRCC4 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

XRCC4 (transcript variant 1)

  Recombinant protein of human X-ray repair complementing defective repair in Chinese hamster cells 4 (XRCC4), transcript variant 1  
XRCC4 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

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