XRCC9 / FANCG antibody

Principal name

XRCC9 / FANCG antibody

Alternative names for XRCC9 / FANCG antibody

FACG, Fanconi anemia group G protein, DNA repair protein XRCC9

SwissProt ID

O15287 (Human), Q9EQR6 (Mouse)

Gene ID

2189 (FANCG)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey), Chimp (Chimpanzee), Can (Canine), Por (Porcine)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Paraffin Sections (P), ELISA (detection) (E(detection))

Background of XRCC9 / FANCG antibody

FANCG (also called Protein FACG or DNA-repair protein XRCC9) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function. FANCG may also be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. This protein may also function as a tumor suppressor gene. FANCG belongs to the multi-subunit Fanconi Anemia (FA) complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. FANCG contains a 5-prime GC-rich untranslated region characteristic of housekeeping genes. The putative 622-amino acid protein has a leucine-zipper motif at its N-terminus. FANCG is mainly found within the nucleus although some protein is localized in the cytoplasm. This protein is highly expressed in testis and thymus and is also found in lymphoblasts. Fanconi anemia is an autosomal recessive disorder with diverse clinical symptoms, including developmental anomalies, bone marrow failure, and early occurrence of malignancies caused by defects in the FANCG gene. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage), and defective DNA repair.

General readings

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Wang, C., et al. Biochemistry 49(26):5560-5569(2010)
Monsees, G.M., et al. Breast Cancer Res. Treat. (2010) In press
Lipkin, S.M., et al. Cancer Prev Res (Phila) 3(5):597-603(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

XRCC9 / FANCG antibody

Immunofluorescence of monoclonal antibody to FANCG on HeLa cell. [antibody concentration 10 ug/ml] Mouse IgG2a 2C8 Purified Hu E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

XRCC9 / FANCG antibody

Detection of FANC G in transfected COS1 cell lysate Rabbit IgG Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

XRCC9 / FANCG antibody

TA302483 (0.5µg/ml) staining of HeLa cell lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

XRCC9 / FANCG (1-12) antibody

WB using Anti-FANCG antibody shows detection of a band at ~69 kDa (arrowhead) corresponding to FANCG present in a HeLa whole cell lysate. The primary antibody was used at a 1:500 dilution. Molecular weight estimation was made by comparison to prestained MW markers (indicated at left). Rabbit IgG Aff - Purified Chimp, Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

XRCC9 / FANCG antibody

ELISA: FANCG Antibody Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

XRCC9 / FANCG (1-12) antibody

AP07583PU-N XRCC9/FANCG antibody staining of 
Formalin-Fixed Paraffin-Embedded Human Thymus at 2.5 µg/ml followed by biotinylated Goat anti-Rabbit IgG secondary antibody, Alkaline Phosphatase-Streptavidin and Chromogen. Rabbit Aff - Purified Hu E, ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

XRCC9 / FANCG (609-622) antibody

Human Spleen (formalin-fixed, paraffin-embedded) stained with FANCG antibody AP22490PU-N at 3 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Goat Aff - Purified Can, Hu, Mky, Prim E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

XRCC9 / FANCG (C-term) antibody

Formalin fixed and paraffin embedded human cerebellum tissue reacted with XRCC9 / FANCG Antibody (C-term) Cat.-No AP51609PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

XRCC9 / FANCG antibody

Western Blot analysis of FANCG expression in transfected 293T cell line (H00002189-T01) by FANCG MaxPab polyclonal antibody.

Lane 1: FANCG transfected lysate(68.42 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

XRCC9 / FANCG antibody

XRCC9 / FANCG Rabbit Serum Hu IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

XRCC9 / FANCG antibody

FANCG MaxPab rabbit polyclonal antibody. Western Blot analysis of FANCG expression in human liver. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

XRCC9 / FANCG antibody

XRCC9 / FANCG Mouse IgG2a 1B2 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

XRCC9 / FANCG antibody

HEK293 overexpressing FANCG and probed with FANCG polyclonal antibody ( Cat # PAB6485 ) ( mock transfection in first lane ), tested by Origene. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

XRCC9 / FANCG antibody

Immunohistochemistry of FANCG polyclonal antibody ( Cat # PAB10048 ) shows strong nuclear and cytoplasmic staining of cells of macrophages in human lung tissue.
Tissue was formalin-fixed and paraffin embedded.
Brown color indicates presence of protein, blue color shows cell nuclei.
Personal Communication, Kenneth Wester, www.proteinatlas.org, Uppsala, Sweden. Chimp, Hu
0.1 mg / €560.00
  Abnova Taiwan Corp.

XRCC9 / FANCG antibody

Western blot analysis of FANCG in transfected COS-1 cell lysate using FANCG polyclonal antibody ( Cat # PAB12371 ). Rabbit IgG Hu WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

XRCC9 / FANCG antibody

ELISA: FANCG Antibody [25350002] Rabbit Hu E
50 µg / €440.00
  Novus Biologicals Inc.

XRCC9 / FANCG antibody

XRCC9 / FANCG Rabbit Serum Hu WB
25 µl / €160.00
  Novus Biologicals Inc.

XRCC9 / FANCG antibody

Western Blot: FANCG Antibody [NBP1-06035] - HEK293 overexpressing FANCG (RC202443) and probed (mock transfection in first lane), tested by Origene. Goat IgG Aff - Purified Hu, Ms E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

XRCC9 / FANCG

XRCC9 / FANCG Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

XRCC9 / FANCG

XRCC9 / FANCG Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

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