XRCC9 / FANCG antibody

Principal name

XRCC9 / FANCG antibody

Alternative names for XRCC9 / FANCG antibody

FACG, Fanconi anemia group G protein, DNA repair protein XRCC9

SwissProt ID

O15287 (Human), Q9EQR6 (Mouse)

Gene ID

2189 (FANCG), 60534 (Fancg)

Available reactivities

Hu (Human), Chimp (Chimpanzee), Can (Canine), Mky (Monkey), Prim (Primate)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of XRCC9 / FANCG antibody

FANCG (also called Protein FACG or DNA-repair protein XRCC9) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function. FANCG may also be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. This protein may also function as a tumor suppressor gene. FANCG belongs to the multi-subunit Fanconi Anemia (FA) complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. FANCG contains a 5-prime GC-rich untranslated region characteristic of housekeeping genes. The putative 622-amino acid protein has a leucine-zipper motif at its N-terminus. FANCG is mainly found within the nucleus although some protein is localized in the cytoplasm. This protein is highly expressed in testis and thymus and is also found in lymphoblasts. Fanconi anemia is an autosomal recessive disorder with diverse clinical symptoms, including developmental anomalies, bone marrow failure, and early occurrence of malignancies caused by defects in the FANCG gene. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage), and defective DNA repair.

General readings

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Wang, C., et al. Biochemistry 49(26):5560-5569(2010)
Monsees, G.M., et al. Breast Cancer Res. Treat. (2010) In press
Lipkin, S.M., et al. Cancer Prev Res (Phila) 3(5):597-603(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

XRCC9 / FANCG antibody

  Rabbit Polyclonal Antibody against FANCG  
Detection of FANC G in transfected COS1 cell lysate Rabbit IgG Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

XRCC9 / FANCG antibody

  Goat Polyclonal Antibody against FANCG / XRCC9  
TA302483 (0.5µg/ml) staining of HeLa cell lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

XRCC9 / FANCG (1-12) antibody

  Rabbit polyclonal anti-FANCG antibody  
WB using Anti-FANCG antibody shows detection of a band at ~69 kDa (arrowhead) corresponding to FANCG present in a HeLa whole cell lysate. The primary antibody was used at a 1:500 dilution. Molecular weight estimation was made by comparison to prestained MW markers (indicated at left). Rabbit IgG Aff - Purified Chimp, Hu E, P, WB
0.1 mg / €356.00
  OriGene Technologies, Inc.

XRCC9 / FANCG antibody

  Rabbit polyclonal FANCG (Phospho-Ser383) antibody  
Western blot analysis of extracts from K562 cells, using FANCG (Phospho-Ser383) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

XRCC9 / FANCG antibody

  Rabbit Polyclonal Anti-Phospho-FANCG(Ser383) Antibody  
Western blot analysis on K562 cell lysate using Phospho-FANCG(Ser383) Antibody Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

XRCC9 / FANCG antibody

  Rabbit Polyclonal FANCG Antibody  
ELISA: FANCG Antibody Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

XRCC9 / FANCG (1-12) antibody

AP07583PU-N XRCC9/FANCG antibody staining of 
Formalin-Fixed Paraffin-Embedded Human Thymus at 2.5 µg/ml followed by biotinylated Goat anti-Rabbit IgG secondary antibody, Alkaline Phosphatase-Streptavidin and Chromogen. Rabbit Aff - Purified Hu E, ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

XRCC9 / FANCG (609-622) antibody

Human Spleen (formalin-fixed, paraffin-embedded) stained with FANCG antibody AP22490PU-N at 3 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Goat Aff - Purified Can, Hu, Mky, Prim E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

XRCC9 / FANCG (C-term) antibody

Formalin fixed and paraffin embedded human cerebellum tissue reacted with XRCC9 / FANCG Antibody (C-term) Cat.-No AP51609PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

FANCG - human gene knockout kit via CRISPR

FANCG - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

FANCG - human gene knockout kit via CRISPR

FANCG - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

FANCG - human gene knockout kit via CRISPR

FANCG - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

FANCG - human gene knockout kit via CRISPR

FANCG - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Fancg - mouse gene knockout kit via CRISPR

Fancg - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Fancg - mouse gene knockout kit via CRISPR

Fancg - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Fancg - mouse gene knockout kit via CRISPR

Fancg - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Fancg - mouse gene knockout kit via CRISPR

Fancg - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, FANCG (mGFP-tagged) - Human Fanconi anemia, complementation group G (FANCG), 200 uL, >10^7 TU/mL

Lenti ORF particles, FANCG (mGFP-tagged) - Human Fanconi anemia, complementation group G (FANCG), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, FANCG (Myc-DDK tagged) - Human Fanconi anemia, complementation group G (FANCG) , 200 uL, >10^7 TU/mL

Lenti ORF particles, FANCG (Myc-DDK tagged) - Human Fanconi anemia, complementation group G (FANCG) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Fancg (GFP-tagged) - Mouse Fanconi anemia, complementation group G (Fancg), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Fancg (GFP-tagged) - Mouse Fanconi anemia, complementation group G (Fancg), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,280.00
  OriGene Technologies, Inc.

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