YPEL3 antibody

Principal name

YPEL3 antibody

Alternative names for YPEL3 antibody

Protein yippee-like 3

Gene ID

83719 (YPEL3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB)

Background of YPEL3 antibody

YPEL3 (yippee-like 3) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division. YPEL3 is a p53-regulated gene whose expression is induced by DNA damage and in turn induces cellular senescence. It appears to function as a tumor suppressor as it is downregulated in colon and breast tumors.

General readings

Kelley K, Miller KR, Todd A, et al. YPEL3, a p53-regulated gene that induces cellular senescence. Cancer Res. 2010; 70:3566-75.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

YPEL3 (N-term) antibody

  Rabbit Polyclonal YPEL3 Antibody  
Western blot analysis of YPEL3 in A-20 cell lysate with YPEL3 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

YPEL3 overexpression lysate

YPEL3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, YPEL3 (mGFP-tagged) - Human yippee-like 3 (Drosophila) (YPEL3), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, YPEL3 (mGFP-tagged) - Human yippee-like 3 (Drosophila) (YPEL3), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

3 Item(s)

per page
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