ZACN / LGICZ antibody

Principal name

ZACN / LGICZ antibody

Alternative names for ZACN / LGICZ antibody

L2, LGICZ1, ZAC, Zinc-activated ligand-gated ion channel, Ligand-gated ion channel zinc-activated 1, Ligand-gated ion-channel receptor L2

SwissProt ID

Q401N2 (Human), Q866Y9 (Canfa)

Gene ID

353174 (ZACN)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Eq (Equine), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB)

Background of ZACN / LGICZ antibody

Over forty homologous proteins belong to the superfamily of ligand-gated ion channels. These members are broken down into different subfamilies, for example: acetylcholine, serotonin and glycine receptors. A new member has been added to this superfamily – ZAC (zinc-activated channel) which is expressed in human and dog but not in rodents. Like all other ligand-gated ion channels, ZAC has four transmembrane domains and extracellular N- and C-termini. As its me states, the channel is activated by high concentrations of zinc. ZAC mR was found to be expressed in placenta, spil cord, stomach, and fetal brain. In another study, ZAC was identified using a computer-assisted program and was detected in similar areas (including pancreas and kidney), but also displayed minor discrepancies. Being that the channel is expressed in human and dog, deciphering its cellular/physiological functions will be challenging.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ZACN / LGICZ antibody

Western blot analysis of Panc-1 (lanes 1 and 3) and Jurkat (lanes 2 and 4) cell lysates: 1, 2. Anti-Zinc-Activated Channel (ZAC) (extracellular) antibody, (1:200). 3, 4. Anti-Zinc-Activated Channel (ZAC) (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Hu WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

ZACN / LGICZ antibody

WB Suggested Anti-LGICZ1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: NCI-H226 cell lysate Rabbit IgG Purified Bov, Can, Eq, Hu, Por, Rb WB
50 µg / €325.00
  OriGene Technologies, Inc.

ZACN / LGICZ antibody

Human NCI-H226; WB Suggested Anti-LGICZ1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: NCI-H226 cell lysate; LGICZ1 antibody - N-terminal region (ARP35525_P050) in Human NCI-H226 cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu WB
50 µg / €350.00
  AVIVA Systems Biology

ZACN / LGICZ antibody

ZACN / LGICZ Rabbit Aff - Purified Bov, Can, Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

ZACN overexpression lysate

ZACN overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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