ZBP1 antibody

Principal name

ZBP1 antibody

Alternative names for ZBP1 antibody

C20orf183, DLM1, Z-DNA-binding protein 1

SwissProt ID

Q8VDA5 (Rat), Q9H171 (Human), Q9QY24 (Mouse)

Gene ID

81030 (ZBP1), 58203 (Zbp1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit, Mouse, Rat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Flow Cytometry (F), Paraffin Sections (P)

Background of ZBP1 antibody

Z-DNA binding protein 1 (ZBP-1) belongs to a family of proteins that contain the Zalpha domain, which binds specifically to left-handed Z-DNA and Z-RAN. Vertebrate ZBPs are induced by immunostimulation and are involved in host defense mechanisms. ZBP-1 initiates an innate immune response by binding to foreign DNA in the cytosol. ZBP-1 mediates activation of the innate immune system by facilitating DNA-mediated induction of type-1 IFN and expression of other related genes. Human ZBP-1 is most prominently expressed in lymphatic tissues. Besides its function in immunoresponse, it is up-regulated in mouse tumor stromal cells and is speculated to play a role in host defense again tumors. 
Structure: 429 amino acids with predicted molecular weight of 46.3 kD.
Distribution: Cytosol.
Function: Participates in the detection of DNA from viral, bacterial, and host origin by the host's innate immune system. Plays a role in host defense against tumors and pathogens. Acts as a cytoplasmic DNA sensor which, when activated, induces the recruitment of TBK1 and IRF3 to its C-terminal region and activates the downstream interferon regulatory factor (IRF) and NF-kappa B transcription factors, leading to type-I interferon production.

General readings

Rothenburg,S., et al., (2002) Nucleic Acids Res. 30 (4), 993-1000

Items 1 to 20 of 23 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ZBP1 (C-term) antibody

  Rabbit Polyclonal ZBP1 Antibody  
Western blot analysis of ZBP1 in mouse small intestine tissue lysate with ZBP1 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ZBP1 antibody

  Rabbit Polyclonal Anti-ZBP1 Antibody  
WB Suggested Anti-ZBP1 Antibody; Titration: 5.0 ug/ml; Positive Control: HepG2 Whole Cell Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ZBP1 antibody

  Rabbit Polyclonal Anti-TRPM3 Antibody  
WB Suggested Anti-TRPM3 Antibody Titration: 2.5 ug/ml; ELISA Titer: 1:312500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ZBP1 antibody

  Rat Monoclonal anti-ZBP-1 Antibody  
Extracts of 293E cells nontransfected (Lane A) and transfected with hZBP-1 (Lane B) were resolved by eletrophoresis, trasferred to nitrocellulose, and probed with anti-hZBP-1 antibody (clone RONOB19). Proteins were visualized using a goat anti-rat IgG secondary conjugated to HRP and chemiluminescence detection. Rat RonoB19 Purified Hu F, ICC/IF, IP, WB
0.1 mg / €280.00
  OriGene Technologies, Inc.

ZBP1 antibody

  Rabbit Polyclonal Z DNA binding protein Antibody  
ELISA: Z DNA binding protein Antibody Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

ZBP1 - human gene knockout kit via CRISPR

ZBP1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

ZBP1 - human gene knockout kit via CRISPR

ZBP1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

ZBP1 - human gene knockout kit via CRISPR

ZBP1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

ZBP1 - human gene knockout kit via CRISPR

ZBP1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ZBP1 (transcript variant 1)

  Recombinant protein of human Z-DNA binding protein 1 (ZBP1), transcript variant 1  
ZBP1 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
10 µg / €299.00
  OriGene Technologies, Inc.

ZBP1 (full length, N-term HIS tag, transcript variant 1)

  Purified recombinant protein of Human Z-DNA binding protein 1 (ZBP1), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug  
ZBP1 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

ZBP1 overexpression lysate

ZBP1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

ZBP1 overexpression lysate

ZBP1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ZBP1 (mGFP-tagged) - Human Z-DNA binding protein 1 (ZBP1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, ZBP1 (mGFP-tagged) - Human Z-DNA binding protein 1 (ZBP1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, ZBP1 (mGFP-tagged) - Human Z-DNA binding protein 1 (ZBP1), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, ZBP1 (mGFP-tagged) - Human Z-DNA binding protein 1 (ZBP1), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €920.00
  OriGene Technologies, Inc.

Lenti ORF particles, ZBP1 (mGFP-tagged)-Human Z-DNA binding protein 1 (ZBP1), transcript variant 4, 200 uL, >10^7 TU/mL

Lenti ORF particles, ZBP1 (mGFP-tagged)-Human Z-DNA binding protein 1 (ZBP1), transcript variant 4, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, ZBP1 (Myc-DDK tagged) - Human Z-DNA binding protein 1 (ZBP1), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, ZBP1 (Myc-DDK tagged) - Human Z-DNA binding protein 1 (ZBP1), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, ZBP1 (Myc-DDK tagged) - Human Z-DNA binding protein 1 (ZBP1), transcript variant 3 , 200 uL, >10^7 TU/mL

Lenti ORF particles, ZBP1 (Myc-DDK tagged) - Human Z-DNA binding protein 1 (ZBP1), transcript variant 3 , 200 uL, >10^7 TU/mL  
200 µl / €820.00
  OriGene Technologies, Inc.

Lenti ORF particles, ZBP1 (Myc-DDK-tagged)-Human Z-DNA binding protein 1 (ZBP1), transcript variant 4, 200 uL, >10^7 TU/mL

Lenti ORF particles, ZBP1 (Myc-DDK-tagged)-Human Z-DNA binding protein 1 (ZBP1), transcript variant 4, 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Zbp1 (GFP-tagged) - Mouse Z-DNA binding protein 1 (Zbp1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Zbp1 (GFP-tagged) - Mouse Z-DNA binding protein 1 (Zbp1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Items 1 to 20 of 23 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn