ZBTB7A / Pokemon antibody

Principal name

ZBTB7A / Pokemon antibody

Alternative names for ZBTB7A / Pokemon antibody

ZBTB7, FBI1, FBI-1, LRF, TIP21, Zinc finger and BTB domain-containing protein 7A, POK (POZ and Krueppel) erythroid myeloid ontogenic factor, Factor binding IST protein 1, Leukemia/lymphoma-related factor, TTF-I-interacting peptide 21

SwissProt ID

O88939 (Mouse), O93567 (Chick), O95365 (Human), Q9QZ48 (Rat)

Gene ID

51341 (ZBTB7A), 16969 (Zbtb7a), 117107

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey), Prim (Primate), Chk (Chicken), African clawed frog, GP (Guinea Pig), Ze (Zebrafish), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Mouse, Goat

Available applications

Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Enzyme Immunoassay (E), Paraffin Sections (P), Frozen Sections (C)

Background of ZBTB7A / Pokemon antibody

Pokemon is a 584 a.a. protein with zinc finger and BTB-POZ domains. It is a member of the POK family of proteins that play important roles in embryonic development, cell lineage determination and differentiation, but are also involved in oncogenesis. Thus Pokemon is amplified or over-expressed in numerous types of cancers, including breast and prostate cancer, lymphoma, small cell lung carcinoma and malignant glioma. It functions as a transcriptional repressor of the p19 arf p53, and RB tumor suppressor genes and works in concert with oncogenes and other proteins associated with the promotion of cell growth. Its overexpression has been shown to cause activation of membrane type 1-matrix metalloproteinase which is associated with adverse outcome in ovarian cancers and increased drug resistance. These properties are thought to impart its role in oncogenesis. In this context, Pokemon is regarded as a marker of aggressive tumors and may thus serve as a useful marker of poor prognosis in cancers. Pokemon is also being reviewed as a target for inhibiting oncogenesis.

General readings

Laudes,M., et al., (2004) J. Biol. Chem. 279 (12), 11711-11718

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ZBTB7A / Pokemon antibody

  Rabbit Polyclonal Anti-ZBTB7A Antibody  
WB Suggested Anti-ZBTB7A Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Hela cell lysate Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

ZBTB7A / Pokemon antibody

Nuclear and cytoplasmic staining of reactive tonsil (Human) is shown on Formalin Fixed Paraffin tissue. The sections were stained at 5 µg/ml with Pokemon Antibody Cat.-No AM32711PU-N (Clone BC17-2.9F) and peroxidase conjugated anti-Mouse Ig secondary antibody with DAB substrate. Mouse IgG1 BC17-2.9F Purified Hu C, ICC/IF, P, WB
0.1 mg / €250.00
  Acris Antibodies GmbH

ZBTB7A / Pokemon antibody

Hum. Adult Placenta; Host:Rabbit. Target Name:ZBTB7A. Sample Tissue:Human Adult Placenta. Antibody Dilution: 1.0ug/ml.; ZBTB7A antibody - N-terminal region (ARP37762_P050) in Hum. Adult Placenta cells using Western Blot Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

ZBTB7A / Pokemon (N-term) antibody

  Rabbit Polyclonal ZBTB7A Antibody  
Western blot analysis of ZBTB7A in human ovary tissue lysate with ZBTB7A antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms E, ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ZBTB7A / Pokemon antibody

  Rabbit Polyclonal Anti-ZBTB7A Antibody  
WB Suggested Anti-ZBTB7A Antibody Titration: 1.25 ug/ml; ELISA Titer: 1:12500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Hu, Ms, Por, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ZBTB7A / Pokemon antibody

  Rabbit Polyclonal Anti-ZBTB7A Antibody  
Host: Rabbit; Target Name: ZBTB7A; Sample Tissue: Liver Tumor lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

ZBTB7A / Pokemon antibody

  Rabbit Polyclonal Anti-ZBTB7A Antibody  
WB Suggested Anti-ZBTB7A Antibody Titration: 5.0 ug/ml; ELISA Titer: 1:1562500; Positive Control: NIH/3T3 cell lysate Rabbit IgG Purified Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ZBTB7A / Pokemon antibody

  Rabbit Polyclonal Anti-ZBTB7A Antibody  
WB Suggested Anti-ZBTB7A Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Hela cell lysate Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Rb, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

ZBTB7A / Pokemon (C-term) antibody

Formalin-Fixed Paraffin-Embedded Human Spleen stained with ZBTB7A / Pokemon antibody Cat.-No AP08834PU-N at 5 µg/ml after heat-induced antigen retrieval. Goat IgG Aff - Purified Hu, Mky, Prim E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

ZBTB7A / Pokemon antibody

Immunofluorescence of purified MaxPab antibody to ZBTB7A on HeLa cell. [antibody concentration 10 ug/ml] Mouse Serum Hu E(detection), ICC/IF, WB
50 µl / €370.00
  Abnova Taiwan Corp.

ZBTB7A / Pokemon antibody

ZBTB7A / Pokemon Mouse IgG2a 2A2 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

ZBTB7A / Pokemon antibody

ZBTB7A / Pokemon Rabbit Hu, Ms IP, WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

ZBTB7A / Pokemon antibody

Human HepG2; WB Suggested Anti-ZBTB7A Antibody Titration: 1.25ug/ml. ELISA Titer: 1:12500. Positive Control: HepG2 cell lysate; ZBTB7A antibody - middle region (ARP35899_T100) in Human HepG2 cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

ZBTB7A / Pokemon antibody

Human HeLa; WB Suggested Anti-ZBTB7A Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Hela cell lysate; ZBTB7A antibody - N-terminal region (ARP39211_P050) in Human HeLa cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

CRISPR

Catalog No. Species Donor Vector  

ZBTB7A - human gene knockout kit via CRISPR

ZBTB7A - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

ZBTB7A - human gene knockout kit via CRISPR

ZBTB7A - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

ZBTB7A - human gene knockout kit via CRISPR

ZBTB7A - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

ZBTB7A - human gene knockout kit via CRISPR

ZBTB7A - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ZBTB7A / Pokemon

  Recombinant protein of human zinc finger and BTB domain containing 7A (ZBTB7A)  
ZBTB7A / Pokemon Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

ZBTB7A / Pokemon

ZBTB7A / Pokemon Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

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