ZBTB7B antibody

Principal name

ZBTB7B antibody

Alternative names for ZBTB7B antibody

ZFP67, Zfp-67, ZBTB15, ZBT-15, Thpok, Th-POK, cKrox, c-Krox, Zinc finger and BTB domain-containing protein 7B, Zinc finger protein 67 homolog, Zinc finger and BTB domain-containing protein 15, T-helper-inducing POZ/Krueppel-like factor

SwissProt ID

O15156 (Human), Q64321 (Mouse)

Gene ID

51043 (ZBTB7B), 22724 (Zbtb7b)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), Eq (Equine), Hst (Hamster), Mky (Monkey), Op (Opossum), Prim (Primate), Xen (Xenopus), Bear, GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit, Mouse, Goat

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of ZBTB7B antibody

Th-POK is a member of the BTB-POZ domain-containing zinc finger transcription factor family. It regulates gene expression during intrathymic T cell differentiation. A single autosomal recessive mutation of the Th-POK gene results in the absence of mature CD4+ helper T cells, called helper-deficient (HD) phenotype. In Th-POK deficient mice, MHC class II restricted thymocytes are redirected to the CD8+ T cell lineage. On the contrary, forced expression of Th-POK redirects MHC class I restricted thymocytes to the CD4+ T cell lineage. Inactivation of Th-POK in mature CD4+ T cells results in induction of the genes preferentially expressed in CD8+ T cells, such as CD8, granzyme B, and IFN-γ. These findings suggest that Th-POK is essential in promoting commitment of immature T cells to the CD4 lineage and maintaining the characteristics of mature CD4+ T helper cells.

General readings

Widom, R.L., et al., (1997) Gene 198 (1-2), 407-420

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ZBTB7B antibody

  Rabbit Polyclonal Anti-ZFP67 Antibody  
WB Suggested Anti-ZFP67 Antibody Titration: 1.0-2.0ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ZBTB7B antibody

  Mouse Monoclonal anti-Th-POK (ZFP-67) Antibody  
Western blot analysis of Hela (lane 1), mouse thymus (lane 2),  MCF-7 (lane 3) and THP-1 (lane 4) cells using anti-Th-POK (ZFP-67) antibody (clone 11H11A14). GAPDH antibody (poly6314) was used as loading control. Mouse 11H11A14 Purified Hu ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ZBTB7B antibody

Immunohistochemical analysis of paraffin-embedded human Breast tissues using anti-ZBTB7B antibody Cat.-No AM06405SU-N Mouse IgG1 7C12 Ascites Hu E, ICC/IF, P, WB
0.1 ml / €400.00
  Acris Antibodies GmbH

ZBTB7B antibody

Western blot using anti-cKrox
antibody to detect endogenous cKrox in mouse thymocyte whole cell lysates. The left lane is a control with no primary antibody. The center lane is a reagent control. The right lane shows a band at 80 kDa corresponding to mouse cKrox protein. The membrane was probed with the primary antibody at a 1:500 dilution. Personal Communication, L. Wang and R. Bossulet, National Cancer Institute, Bethesda, MD. Rabbit IgG Serum Hu, Ms, Rt E, WB
0.1 ml / €450.00
  Acris Antibodies GmbH

ZBTB7B (Center) antibody

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ZBTB7B antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

ZBTB7B (365-377) antibody

Testis, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat Aff - Purified Bear, Bov, Can, Eq, Hst, Hu, Mky, Ms, Op, Prim, Rt, Xen P
50 µg / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

ZBTB7B - human gene knockout kit via CRISPR

ZBTB7B - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

ZBTB7B - human gene knockout kit via CRISPR

ZBTB7B - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ZBTB7B (mGFP-tagged)-Human zinc finger and BTB domain containing 7B (ZBTB7B), 200 uL, >10^7 TU/mL

Lenti ORF particles, ZBTB7B (mGFP-tagged)-Human zinc finger and BTB domain containing 7B (ZBTB7B), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, ZBTB7B (Myc-DDK-tagged)-Human zinc finger and BTB domain containing 7B (ZBTB7B), 200 uL, >10^7 TU/mL

Lenti ORF particles, ZBTB7B (Myc-DDK-tagged)-Human zinc finger and BTB domain containing 7B (ZBTB7B), 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Zbtb7b (GFP-tagged) - Mouse zinc finger and BTB domain containing 7B (Zbtb7b), 200 uL, >10^7 TU/mL

Lenti ORF particles, Zbtb7b (GFP-tagged) - Mouse zinc finger and BTB domain containing 7B (Zbtb7b), 200 uL, >10^7 TU/mL  
200 µl / €1,170.00
  OriGene Technologies, Inc.

Lenti ORF particles, Zbtb7b (Myc-DDK-tagged) - Mouse zinc finger and BTB domain containing 7B (Zbtb7b), 200 uL, >10^7 TU/mL

Lenti ORF particles, Zbtb7b (Myc-DDK-tagged) - Mouse zinc finger and BTB domain containing 7B (Zbtb7b), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

12 Item(s)

per page
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