ZC3H12A antibody

Principal name

ZC3H12A antibody

Alternative names for ZC3H12A antibody

MCPIP, MCPIP1, Zinc finger CCCH domain-containing protein 12A, Ribonuclease ZC3H12A, MCP-induced protein 1

SwissProt ID

A0JPN4 (Rat), A6QQJ8 (Bovin), Q5D1E7 (Mouse), Q5D1E8 (Human)

Gene ID

80149 (ZC3H12A)

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Rabbit

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Immunoprecipitation (IP)

Background of ZC3H12A antibody

ZC3H12A, also known as MCPIP, is an essential member of a family of novel CCCH-zinc finger proteins that regulate macrophage activation and may be involved in host immunity and inflammatory diseases. ZC3H12A has RNase activity that prevents some immune disorders by directly affecting the mRNA stability of interleukins such as IL-6 and IL12p40. Mice lacking the ZC3H12A gene suffered from severe anemia, and most dies within 12 weeks. Overexpression of ZC3H12A causes ER stress and induces a number of genes involved in apoptosis and autophagy, including JNK, PUMA, and beclin-1 in cardiac myoblasts, leading to cell death. ZC3H12A can also induce adipogenesis in 3T3-L1 pre-adipocytes in the absence of PPAPgamma, demonstrating the complex roles ZC3H12A plays.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ZC3H12A antibody

Western blot analysis of ZC3H12A in Raji cell lysate with ZC3H12A antibody at (A) 1 and (B) 2 µg/ml. Rabbit IgG Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ZC3H12A antibody

ZC3H12A antibody [N3C3] detects ZC3H12A protein by western blot analysis. A. 30 ug 293T whole cell extract. B. 30 ug A431 whole cell extract. C. 30 ug HeLa whole cell extract. D. 30 ug HepG2 whole cell extract. 7.5 % SDS-PAGE. ZC3H12A antibody [N3C3] (TA3 Rabbit IgG Aff - Purified Hu, Ms ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ZC3H12A Control Peptide

ZC3H12A
50 µg / €160.00
  Acris Antibodies GmbH

ZC3H12A (Center) antibody

ZC12A antibody (Center) (AP54619PU-N) immunohistochemistry analysis in formalin fixed and paraffin embedded human spleen tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ZC12A antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

ZC3H12A antibody

Western Blot: ZC3H12A Antibody [NBP1-76258] - Analysis of ZC3H12A in Raji cell lysate with ZC3H12A antibody at (A) 1 and (B) 2 ug/mL._x000d_ Rabbit Aff - Purified Hu E, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

ZC3H12A antibody

Immunohistochemistry-Paraffin: ZC3H12A Antibody [NBP1-83587] - Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in tubules. Rabbit IgG Aff - Purified Hu ICC/IF, P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ZC3H12A

ZC3H12A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

ZC3H12A

ZC3H12A Human
10 µg / €380.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

ZC3H12A overexpression lysate

ZC3H12A overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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