ZFYVE21 antibody

Principal name

ZFYVE21 antibody

Alternative names for ZFYVE21 antibody

Zinc finger FYVE domain-containing protein 21

SwissProt ID

Q05B78 (Bovin), Q8VCM3 (Mouse), Q9BQ24 (Human)

Gene ID

79038 (ZFYVE21)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E)

Background of ZFYVE21 antibody

ZF21 Antibody: ZF21 was initially identified as protein that could bind to the cytoplasmic tail of MT1-MMP (Membrane-type 1 matrix metalloproteise), a potent invasion-promoting protease. ZF21 is a member of a protein family characterized by the presence of a phosphatidylinositol 3-phosphate-binding FYVE domain and regulates focal adhesions (FAs) and cell movement. Knockdown of ZF21 expression resulted in a delay of FA disassembly following induction of synchronous disassembly of FAs by nocodazole treatment, suggesting that ZF21 is involved in FA disassembly. ZF21 contains a noncanonical pleckstrin homology domain that is a possible therapeutic target to treat metastatic cancer.

General readings

Uekita T, Gotoh I, Kinoshita T, et al. Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein-1 is a new member of the Cupin superfamily. A possible multifunctional protein acting as an invasion suppressor down-regulated in tumors. J. Biol. Chem. 2004; 279:12734-43.
Nagano M, Hoshino D, Sakamoto T, et al. ZF21 protein regulates cell adhesion and motility. J. Biol. Chem. 2010; 285:21013-22.
Nagano M, Hoshino D, Koshiba S, et al. ZF21 protein, a regulator of the disassembly of focal adhesions and cancer metastasis, contains a novel noncanonical pleckstrin homology domain. J. Biol. Chem. 2011; 286:31598-609.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ZFYVE21 (N-term) antibody

Western blot analysis of ZF21 in 3T3 cell tissue lysate with ZF21 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ZFYVE21 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ZFYVE21 (RC203337, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ZFYVE21. Mouse IgG1 OTIB12 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ZFYVE21 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ZFYVE21 (RC203337, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ZFYVE21. Mouse IgG1 OTIA2 Purified Hu WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

ZFYVE21 (N-term) Control Peptide

Western blot analysis in 3T3 cell tissue lysate with ZFYVE21 / ZF21 antibody Cat.-No AP55438PU-N at 1 ?g/ml in (A) the absence and (B) the presence of blocking peptide.
50 µg / €160.00
  Acris Antibodies GmbH

ZFYVE21 antibody

Western Blot analysis of ZFYVE21 expression in transfected 293T cell line by ZFYVE21 MaxPab polyclonal antibody.

Lane 1: ZFYVE21 transfected lysate(25.74 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ZFYVE21

ZFYVE21 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

ZFYVE21

ZFYVE21 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

ZFYVE21

ZFYVE21 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

ZFYVE21 293T Cell Transient Overexpression Lysate(Denatured)

ZFYVE21 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

Lysates (Overexpressed)

Catalog No.    

ZFYVE21 overexpression lysate

ZFYVE21 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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