ZIC1 antibody

Principal name

ZIC1 antibody

Alternative names for ZIC1 antibody

ZIC, Zinc finger protein ZIC 1, Zinc finger protein of the cerebellum 1

SwissProt ID

P46684 (Mouse), Q15915 (Human)

Gene ID

7545 (ZIC1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Chk (Chicken), Bov (Bovine), Eq (Equine), Por (Porcine)

Available hosts

Rabbit, Mouse, Goat

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of ZIC1 antibody

The Zic-1 gene, which encodes a zinc finger protein, is expressed in the developing or matured central nervous system in a highly restricted manner. The Zic gene is expressed in granule cells that make synaptic contact with Purkinje cells. Clearly Zic-1 is a gene critical to cerebellar pattern formation. The expression of Zic genes is first detected at gastrulation and at neurulation, becomes restricted to the dorsal neural ectoderm and the dorsal paraxial mesoderm. Zic-2 and Zic-3 are highly similar genes, especially in their product's zinc finger motif and by comparison of their genomic organization in that they share common exon-intron boundaries and belong to the same gene family. By comparison in function, Zic-2 is essential for the formation of the brain and Zic-3 is important for right and left axis formation. The Zic-1 gene has been mapped to chromosome 9 in mouse. The 5' flanking region of the Zic-1 gene contains a region-specific enhancer determined to be essential in in vivo and in vitro deletion analysis. The temporal profile of mRNA expression differs for each of the Zic gene products. The Drosophila odd-paired gene is highly homologous to the Zic gene family.

General readings

Aruga, J., et al. (1996). The mouse zic gene family. Homologues of the Drosophila pair-rule gene odd-paired. J. Biol. Chem. 12;271(2): 1043-7.
Mikoshiba, K., (1999). Mamalian neural induction and brain pattern formation. Keio J. Med. Sep48(3): 111-23.
Nagai, T. et al., (1997). The expression of the mouse Zic1, Zic2, and Zic3 gene suggests an essential role for Zic genes in body pattern formation. Dev. Biol. Feb15;182(2): 299-313.
Aruga, J. et al., (2000). A 5' segment of the mouse zic1 gene contains a region specific enhancer for dorsal hindbrain and spinal cord. Brain Res. Mol. Brain Res.31;78(1-2): 15-25.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ZIC1 antibody

Western blot analysis of extracts from Jurkat cells and COLO cells, using ZIC1/2/3 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ZIC1 antibody

WB Suggested Anti-ZIC1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:12500; Positive Control: ACHN cell lysate Rabbit IgG Purified Bov, Eq, Hu, Ms, Por, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

ZIC1 antibody

Western Blot: Zic1 Antibody [TA336688] - WB analysis of Zic1 in overexpression lysate. Rabbit Purified Hu, Ms C, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ZIC1 antibody

Western blot analysis on Jurkat cell lysate using ZIC1/2/3 Antibody Rabbit IgG Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ZIC1 antibody

Immunohistochemistry (IHC) analyzes of Zic1/2/3 antibody (Cat.-No.: AP20514PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

ZIC1 (N-term) antibody

ZIC1 Antibody (N-term) (AP54655PU-N) western blot analysis in HL-60 cell line lysates (35 µg/lane). This demonstrates the ZIC1 antibody detected the ZIC1 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

ZIC1 antibody

ZIC1 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

ZIC1 antibody

Detection limit for recombinant GST tagged ZIC1 is approximately 0.3ng/ml as a capture antibody. Mouse IgG 3F7 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ZIC1 antibody

Detection limit for recombinant GST tagged ZIC1 is approximately 1ng/ml as a capture antibody. Mouse IgG 2D3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ZIC1 antibody

Detection limit for recombinant GST tagged ZIC1 is approximately 1ng/ml as a capture antibody. Mouse IgG2b 4D11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ZIC1 antibody

Detection limit for recombinant GST tagged ZIC1 is approximately 0.1ng/ml as a capture antibody. Mouse IgG2a 1D12 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ZIC1 antibody

ZIC1 Mouse IgG2a 1D12 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

ZIC1 antibody

Detection limit for recombinant GST tagged ZIC1 is approximately 0.1ng/ml as a capture antibody. Mouse IgG2a 3C1 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ZIC1 antibody

ZIC1 Mouse IgG2a 3C1 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

ZIC1 antibody

ZIC1 Mouse IgG2a 4D2 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ZIC1 antibody

ZIC1 Mouse IgG2a 1B2 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ZIC1 antibody

ZIC1 Mouse IgG2b 1A8 Purified Hu, Rt E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ZIC1 antibody

ZIC1 Mouse IgG2b 2F6 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ZIC1 antibody

ZIC1 Mouse IgG2a 1E6 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ZIC1 antibody

ZIC1 Mouse IgG2b 3F19 Purified Hu, Rt E, WB
50 µg / €370.00
  Abnova Taiwan Corp.

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