ZNF278 antibody

Principal name

ZNF278 antibody

Alternative names for ZNF278 antibody

Zinc finger protein 278, PATZ1, PATZ, RIAZ, ZBTB19, ZSG, POZ-, AT hook-, and zinc finger-containing protein 1, BTB-POZ domain zinc finger transcription factor, Protein kinase A RI subunit alpha-associated protein, Zinc finger and BTB domain-containing protein 19, Zinc finger sarcoma gene protein

SwissProt ID

Q9HBE1 (Human)

Gene ID

23598 (PATZ1)

Available reactivities

Hu (Human), Can (Canine), Chk (Chicken), Ms (Mouse), Rb (Rabbit), Rt (Rat), African clawed frog, Bov (Bovine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of ZNF278 antibody

PATZ1 contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1;22)(p36.1;q12).The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1;22)(p36.1;q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene.

General readings

Fedele,M., (2008) J. Pathol. 215 (1), 39-47

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ZNF278 antibody

  Rabbit Polyclonal Anti-PATZ1 Antibody  
WB Suggested Anti-PATZ1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: OVCAR-3 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

ZNF278 antibody

  Rabbit Polyclonal Anti-PATZ1 Antibody  
Host: Rabbit; Target Name: PATZ1; Sample Tissue: Human Fetal Lung; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

ZNF278 antibody

  Rabbit Polyclonal Anti-PATZ1 Antibody  
WB Suggested Anti-PATZ1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: HepG2 cell lysate; PATZ1 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

ZNF278 antibody

  Rabbit Polyclonal PATZ Antibody  
ELISA: PATZ Antibody Rabbit IgG Purified Hu E
50 µg / €325.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ZNF278 (full length, N-term HIS tag, transcript variant 4)

  Recombinant protein of human POZ (BTB) and AT hook containing zinc finger 1 (PATZ1), transcript variant 4, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug  
ZNF278 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

ZNF278 (full length, N-term HIS tag, transcript variant 1)

  Purified recombinant protein of Human POZ (BTB) and AT hook containing zinc finger 1 (PATZ1), transcript variant 1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug  
ZNF278 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

PATZ1 overexpression lysate

PATZ1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PATZ1 (mGFP-tagged)-Human POZ (BTB) and AT hook containing zinc finger 1 (PATZ1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, PATZ1 (mGFP-tagged)-Human POZ (BTB) and AT hook containing zinc finger 1 (PATZ1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,550.00
  OriGene Technologies, Inc.

Lenti ORF particles, PATZ1 (mGFP-tagged)-Human POZ (BTB) and AT hook containing zinc finger 1 (PATZ1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, PATZ1 (mGFP-tagged)-Human POZ (BTB) and AT hook containing zinc finger 1 (PATZ1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,300.00
  OriGene Technologies, Inc.

Lenti ORF particles, PATZ1 (mGFP-tagged) - Human POZ (BTB) and AT hook containing zinc finger 1 (PATZ1), transcript variant 4, 200 uL, >10^7 TU/mL

Lenti ORF particles, PATZ1 (mGFP-tagged) - Human POZ (BTB) and AT hook containing zinc finger 1 (PATZ1), transcript variant 4, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, PATZ1 (Myc-DDK-tagged)-Human POZ (BTB) and AT hook containing zinc finger 1 (PATZ1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, PATZ1 (Myc-DDK-tagged)-Human POZ (BTB) and AT hook containing zinc finger 1 (PATZ1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,390.00
  OriGene Technologies, Inc.

Lenti ORF particles, PATZ1 (Myc-DDK-tagged)-Human POZ (BTB) and AT hook containing zinc finger 1 (PATZ1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, PATZ1 (Myc-DDK-tagged)-Human POZ (BTB) and AT hook containing zinc finger 1 (PATZ1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,170.00
  OriGene Technologies, Inc.

Lenti ORF particles, PATZ1 (Myc-DDK tagged) - Human POZ (BTB) and AT hook containing zinc finger 1 (PATZ1), transcript variant 4 , 200 uL, >10^7 TU/mL

Lenti ORF particles, PATZ1 (Myc-DDK tagged) - Human POZ (BTB) and AT hook containing zinc finger 1 (PATZ1), transcript variant 4 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

13 Item(s)

per page
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