ZNF281 antibody

Principal name

ZNF281 antibody

Alternative names for ZNF281 antibody

Zinc finger protein 281, GZP1, ZBP99, ZBP-99, Zinc finger DNA-binding protein 99, GC-box-binding zinc finger protein 1

SwissProt ID

Q9Y2X9 (Human)

Gene ID

23528 (ZNF281)

Available reactivities

Hu (Human), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Bov (Bovine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of ZNF281 antibody

ZFP281, also known as ZBP-99, is a member of a conserved family of transcription factors that interact with GC-rich promoters. It contains four Kruppel-like zinc fingers and is highly homologous to ZBP-89, another regulator of ornithine decarboxylase gene expression. ZFP281 also interacts with many other other transcription factors, such as Sp1 to repress vimentin gene transcription. ZFP281 has also been shown to control embryonic stem cell pluripotency by direct regulating specific target genes. ZFP281 phyically interacts with the transcription factos POU5F1, Sox2, and NANOG. Gene expression microarray anlysis indicated that some ZFP281 target genes were activated, while others were repressed upon knockdown of ZFP281 expression, showing that ZFP281 plays bifuctinal roles in regulating gene expression in stem cells.

General readings

Law,D.J., (1999) Biochem. Biophys. Res. Commun. 262 (1), 113-120

4 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ZNF281 (C-term) antibody

  Rabbit Polyclonal ZFP281 Antibody  
Western blot analysis of ZFP281 in A-20 cell lysate with ZFP281 antibody at (A) 0.25 and (B) 0.5 ug/mL. Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ZNF281 antibody

  Rabbit Polyclonal Anti-ZNF281 Antibody  
WB Suggested Anti-ZNF281 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Hela cell lysate Rabbit IgG Purified Bov, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

ZNF281 antibody

  Rabbit Polyclonal Anti-DARS Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using (ZNF281 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200) Rabbit IgG Purified Hu, Ms E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

ZNF281 overexpression lysate

ZNF281 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

4 Item(s)

per page
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