ZP3A / ZP3B antibody

Principal name

ZP3A / ZP3B antibody

Alternative names for ZP3A / ZP3B antibody

ZP3, ZP-3, ZPC, Zona pellucida sperm-binding protein 3, Zona pellucida glycoprotein ZP3, Zona pellucida protein C, Sperm receptor

SwissProt ID

P10761 (Mouse), P21754 (Human), P42098 (Pig), P48830 (Bovin), P48833 (Rabit), P97708 (Rat)

Gene ID

7784 (ZP3), 22788 (Zp3), 114639

Available reactivities

Bov (Bovine), Hu (Human), Rb (Rabbit)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB)

Background of ZP3A / ZP3B antibody

The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene is a structural component of the zona pellucida and functions in primary binding and induction of the sperm acrosome reaction. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a C-terminal consensus furin cleavage site, and a transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. A variation in the last exon of this gene has previously served as the basis for an additional ZP3 locus; however, sequence and literature review reveals that there is only one full-length ZP3 locus in the human genome. Another locus encoding a bipartite transcript designated POMZP3 contains a duplication of the last four exons of ZP3, including the above described variation, and maps closely to this gene

General readings

Chamberlin,M.E., et al., (1990) Proc. Natl. Acad. Sci. U.S.A. 87 (16), 6014-6018

16 Item(s)

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CRISPR

Catalog No. Species Donor Vector  

ZP3 - human gene knockout kit via CRISPR

ZP3 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

ZP3 - human gene knockout kit via CRISPR

ZP3 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

ZP3 - human gene knockout kit via CRISPR

ZP3 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

ZP3 - human gene knockout kit via CRISPR

ZP3 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Zp3 - mouse gene knockout kit via CRISPR

Zp3 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Zp3 - mouse gene knockout kit via CRISPR

Zp3 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Zp3 - mouse gene knockout kit via CRISPR

Zp3 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Zp3 - mouse gene knockout kit via CRISPR

Zp3 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ZP3 (mGFP-tagged) - Human zona pellucida glycoprotein 3 (sperm receptor) (ZP3), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, ZP3 (mGFP-tagged) - Human zona pellucida glycoprotein 3 (sperm receptor) (ZP3), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,020.00
  OriGene Technologies, Inc.

Lenti ORF particles, ZP3 (mGFP-tagged) - Human zona pellucida glycoprotein 3 (sperm receptor) (ZP3), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, ZP3 (mGFP-tagged) - Human zona pellucida glycoprotein 3 (sperm receptor) (ZP3), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, ZP3 (Myc-DDK tagged) - Human zona pellucida glycoprotein 3 (sperm receptor) (ZP3), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, ZP3 (Myc-DDK tagged) - Human zona pellucida glycoprotein 3 (sperm receptor) (ZP3), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €910.00
  OriGene Technologies, Inc.

Lenti ORF particles, ZP3 (Myc-DDK tagged) - Human zona pellucida glycoprotein 3 (sperm receptor) (ZP3), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, ZP3 (Myc-DDK tagged) - Human zona pellucida glycoprotein 3 (sperm receptor) (ZP3), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Zp3 (GFP-tagged) - Mouse zona pellucida glycoprotein 3 (Zp3), 200 uL, >10^7 TU/mL

Lenti ORF particles, Zp3 (GFP-tagged) - Mouse zona pellucida glycoprotein 3 (Zp3), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Zp3 (Myc-DDK-tagged) - Mouse zona pellucida glycoprotein 3 (Zp3), 200 uL, >10^7 TU/mL

Lenti ORF particles, Zp3 (Myc-DDK-tagged) - Mouse zona pellucida glycoprotein 3 (Zp3), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Zp3 (GFP-tagged ORF) - Rat zona pellucida glycoprotein 3 (sperm receptor) (Zp3), 200 uL, >10^7 TU/mL

Lenti ORF particles, Zp3 (GFP-tagged ORF) - Rat zona pellucida glycoprotein 3 (sperm receptor) (Zp3), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Zp3 (Myc-DDK-tagged ORF) - Rat zona pellucida glycoprotein 3 (sperm receptor) (Zp3), 200 uL, >10^7 TU/mL

Lenti ORF particles, Zp3 (Myc-DDK-tagged ORF) - Rat zona pellucida glycoprotein 3 (sperm receptor) (Zp3), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

16 Item(s)

per page
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