ZP4 / ZPB antibody

Principal name

ZP4 / ZPB antibody

Alternative names for ZP4 / ZPB antibody

Zona pellucida sperm-binding protein 4, Zona pellucida protein B

SwissProt ID

Q12836 (Human), Q8CH34 (Rat), Q9BH11 (Bovin)

Gene ID

57829 (ZP4), 282833 (Zp4)

Available reactivities

Hu (Human), Rt (Rat), Mky (Monkey), Ms (Mouse)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of ZP4 / ZPB antibody

The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix.The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. Previously, this gene has been referred to as ZP1 or ZPB and thought to have similar functions as mouse Zp1. However, a human gene with higher similarity and chromosomal synteny to mouse Zp1 has been assigned the symbol ZP1 and this gene has been assigned the symbol ZP4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Gregory,S.G., (2006) Nature 441 (7091), 315-321

15 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ZP4 / ZPB antibody

Western blot analysis of extracts from Jurkat cells, using ZP4 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ZP4 / ZPB antibody

WB Suggested Anti-ZP4 Antibody Titration: 0.2-1 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

ZP4 / ZPB (C-term) antibody

ZP4 Antibody (C-term) (AP54737PU-N) western blot analysis in HepG2 cell line lysates (35 µg/lane). This demonstrates the ZP4 antibody detected the ZP4 protein (arrow). Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

ZP4 / ZPB antibody

Western blot analysis of extracts from Jurkat cells, using ZP4 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Rt E, WB
50 µg / €205.00
  Assay Biotech

ZP4 / ZPB antibody

Western blot analysis of extracts from Jurkat cells, using ZP4 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

ZP4 / ZPB antibody

recombinant human ZP4 protein; ZP4 antibody - N-terminal region (ARP49639_P050) in recombinant human ZP4 protein cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

ZP4 / ZPB antibody

Western blot analysis of ZP4 expression in HepG2 (A); Hela (B); NIH3T3 (C); H9C2 (D) whole cell lysates. Rabbit Aff - Purified Hu, Mky, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

ZP4 / ZPB antibody

Western blot analysis of ZP4 expression in HepG2 (A); Hela (B); NIH3T3 (C); H9C2 (D) whole cell lysates. Rabbit Aff - Purified Hu, Mky, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

ZP4 / ZPB antibody

Western blot analysis of ZP4 expression in HepG2 (A); Hela (B); NIH3T3 (C); H9C2 (D) whole cell lysates. Rabbit Aff - Purified Hu, Mky, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

CRISPR

Catalog No. Species Donor Vector  

ZP4 - human gene knockout kit via CRISPR

ZP4 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

ZP4 - human gene knockout kit via CRISPR

ZP4 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

ZP4 - human gene knockout kit via CRISPR

ZP4 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

ZP4 - human gene knockout kit via CRISPR

ZP4 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Zp4 (GFP-tagged ORF) - Rat zona pellucida glycoprotein 4 (Zp4), 200 uL, >10^7 TU/mL

Lenti ORF particles, Zp4 (GFP-tagged ORF) - Rat zona pellucida glycoprotein 4 (Zp4), 200 uL, >10^7 TU/mL  
200 µl / €1,180.00
  OriGene Technologies, Inc.

Lenti ORF particles, Zp4 (Myc-DDK-tagged ORF) - Rat zona pellucida glycoprotein 4 (Zp4), 200 uL, >10^7 TU/mL

Lenti ORF particles, Zp4 (Myc-DDK-tagged ORF) - Rat zona pellucida glycoprotein 4 (Zp4), 200 uL, >10^7 TU/mL  
200 µl / €1,055.00
  OriGene Technologies, Inc.

15 Item(s)

per page
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