ZW10 antibody

Principal name

ZW10 antibody

Alternative names for ZW10 antibody

Centromere/kinetochore protein zw10 homolog

SwissProt ID

O43264 (Human), O54692 (Mouse), Q4V8C2 (Rat)

Gene ID

9183 (ZW10)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P)

Background of ZW10 antibody

The mitotic checkpoint ensures that chromosomes are divided equally between daughter cells and is a primary mechanism preventing the chromosome instability often seen in aneuploid human tumors. This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. The encoded protein binds to centromeres during the prophase, metaphase, and early anaphase cell division stages and to kinetochore microtubules during metaphase. It is part of the MIS12 complex, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis. In mitotic human cells ZW10 resides in a complex with Rod and Zwilch, whereas another ZW10 partner, Zwint-1, is part of a separate complex of structural kinetochore components including Mis12 and Ndc80-Hec1. Zwint-1 is critical for recruiting ZW10 to unattached kinetochores. Depletion from human cells demonstrates that the ZW10 complex is essential for stable binding of a Mad1-Mad2 complex to unattached kinetochores. Thus, ZW10 functions as a linker between the core structural elements of the outer kinetochore and components that catalyze generation of the mitotic checkpoint-derived "stop anaphase" inhibitor.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ZW10 antibody

WB Suggested Anti-ZW10 Antibody Titration: 0.2-1 ug/ml; Positive Control: PANC1 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Por, Rb WB
50 µg / €325.00
  OriGene Technologies, Inc.

ZW10 (N-term) antibody

ZW10 Antibody (N-term) (AP54743PU-N) western blot analysis in mouse stomach tissue lysates (35 µg/lane).This demonstrates the ZW10 antibody detected the ZW10 protein (arrow). Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

ZW10 antibody

ZW10 MaxPab polyclonal antibody. Western Blot analysis of ZW10 expression in human placenta. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

ZW10 antibody

Western Blot analysis of ZW10 expression in transfected 293T cell line (H00009183-T02) by ZW10 MaxPab polyclonal antibody.

Lane 1: ZW10 transfected lysate(88.80 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

ZW10 antibody

Western Blot analysis of ZW10 expression in transfected 293T cell line by ZW10 monoclonal antibody (M05), clone 2E5.

Lane 1: ZW10 transfected lysate(88.8 KDa).
Lane 2: Non-transfected lysate. Mouse IgG2a 2E5 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ZW10 antibody

Human PANC1; WB Suggested Anti-ZW10 Antibody Titration: 0.2-1 ug/ml. Positive Control: PANC1 cell lysate; ZW10 antibody - N-terminal region (ARP58358_P050) in Human PANC1 cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

ZW10 antibody

Western Blot: ZW10 Antibody [NBP1-55252] - This Anti-ZW10 antibody was used in Western Blot of PANC1       tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ZW10

ZW10 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

ZW10

ZW10 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

ZW10

ZW10 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

ZW10 293T Cell Transient Overexpression Lysate(Denatured)

ZW10 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

ZW10 overexpression lysate

ZW10 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

12 Item(s)

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