Zygin-1 antibody

Principal name

Zygin-1 antibody

Alternative names for Zygin-1 antibody

Zygin I, FEZ1, Fasciculation and elongation protein zeta-1

SwissProt ID

P97577 (Rat), Q8K0X8 (Mouse), Q99689 (Human)

Gene ID

9638 (FEZ1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine)

Available hosts

Mouse, Goat, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), EPair for Elisa (EPair), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Zygin-1 antibody

Frequent loss of heterozygosity (LOH) at human chromosome 8p22-p21 is associated with various tumors including prostate and breast cancer. The 8p22-p21 region contains the FEZ1 gene, which is altered in tumors of the esophagus, prostate and breast. The FEZ1 protein (also known as leucine zipper putative tumor suppressor or LZTS1) contains a DNA-binding leucine zipper motif. FEZ1 is expressed in normal breast and prostate, but alterations in FEZ1 expression result in abnormal cell growth. The absence of FEZ1 expression is characteristic of breast and prostate cancer cell lines as well as primary breast and pro-state tumors. This absence of FEZ1 may be due to several factors, including mutations in the FEZ1 gene or hypermethylation of the CpG island flanking the FEZ1 promoter region. FEZ1 acts as a negative regulator of cell growth. During cell-cycle progression, FEZ1 localizes to microtubule components and is hyperphosphorylated by cAMP-dependent kinase.

General readings

Suzuki T, Okada Y, Semba S, Orba Y, Yamanouchi S, Endo S, Tanaka S, Fujita T, Kuroda S, Nagashima K, Sawa H. Identification of FEZ1 as a protein that interacts with JC virus agnoprotein and microtubules: role of agnoprotein-induced dissociation of FEZ1 from microtubules in viral propagation.J Biol Chem. 2005 Jul 1;280(26):24948-56. Epub 2005 Apr 20. PMID: 15843383

18 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Zygin-1 antibody

TA303166 (0.03µg/ml) staining of Human Brain (frontal Cortex) lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Can, Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Zygin-1 antibody

Western blot analysis of FEZ1 in SK-N-SH cell lysate with FEZ1 antibody at 1 µg/ml in the (A) presence and (B) absence of blocking peptide. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Zygin-1 (278-290) antibody

Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with FEZ1 antibody AP22574PU-N followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Goat Aff - Purified Bear, Bov, Bt, Can, Elephant, Eq, Fi, Hst, Hu, Mky, Ms, Op, Platypus, Por, Prim, Rb, Rt, Xen E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Zygin-1 Control Peptide

Zygin-1
50 µg / €160.00
  Acris Antibodies GmbH

Zygin-1 antibody

Western Blot analysis of FEZ1 expression in transfected 293T cell line (H00009638-T01) by FEZ1 MaxPab polyclonal antibody.

Lane 1: FEZ1 transfected lysate(43.23 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

Zygin-1 antibody

Western Blot analysis of FEZ1 expression in transfected 293T cell line (H00009638-T02) by FEZ1 MaxPab polyclonal antibody.

Lane 1: FEZ1 transfected lysate(43.12 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Zygin-1 antibody

Western Blot analysis of FEZ1 expression in transfected 293T cell line (H00009638-T03) by FEZ1 MaxPab polyclonal antibody.

Lane 1: FEZ1 transfected lysate(45.10 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Zygin-1 antibody

FEZ1 polyclonal antibody ( Cat # PAB7151 ) ( 0.03 µg/ml ) staining of human brain ( frontal cortex ) lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Zygin-1 antibody

Western blot analysis of FEZ1 in SK-N-SH cell lysate with FEZ1 polyclonal antibody ( Cat # PAB13004 ) at 1 µg/ml in the ( A ) presence and ( B ) absence of blocking peptide. Rabbit Hu, Ms, Rt WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

Zygin-1 antibody

Western Blot: FEZ1 Antibody [NB100-53816] - NB100-53816 (0.03ug/ml) staining of Human Brain (frontal Cortex) lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Zygin-1 antibody

Western Blot: FEZ1 Antibody [NBP1-76395] - Analysis of FEZ1 in SK-N-SH cell lysate with FEZ1 antibody at 1 ug/mL in the (A) presence and (B) absence of blocking peptide._x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Zygin-1 antibody

Immunohistochemistry-Paraffin: FEZ1 Antibody [NBP1-86256] - Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in tubules. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Zygin-1

Zygin-1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

Zygin-1

Zygin-1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Antibody Pairs

Catalog No.    

FEZ1 (Human) Matched Antibody Pair

FEZ1 (Human) Matched Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

FEZ1 293T Cell Transient Overexpression Lysate(Denatured)

FEZ1 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

FEZ1 293T Cell Transient Overexpression Lysate(Denatured)

FEZ1 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

Lysates (Overexpressed)

Catalog No.    

FEZ1 overexpression lysate

FEZ1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

18 Item(s)

per page
  • LinkedIn