Zyxin antibody

Principal name

Zyxin antibody

Alternative names for Zyxin antibody

Zyxin-2, ZYX

SwissProt ID

Q04584 (Chick), Q15942 (Human), Q62523 (Mouse)

Gene ID

7791 (ZYX), 22793 (Zyx)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Rt (Rat), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection))

Background of Zyxin antibody

TRIM50 is an E3 ubiquitin-protein ligase.Focal adhesions are actin-rich structures that eble cells to adhere to the extracellular matrix and at which protein complexes involved in sigl transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-termil proline-rich domain and three LIM domains in its C-termil half. The proline-rich domain may interact with SH3 domains of proteins involved in sigl transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the sigl transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Altertive splicing results in multiple transcript variants that encode the same isoform.

General readings

Li B, Zhuang L, Trueb B, Zyxin interacts with the SH3 domains of the cytoskeletal proteins LIM-nebulette and Lasp-1. The Journal of biological chemistry 2004 May 279 (19): 20401-10.

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Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Zyxin (transcript variant 1)

Zyxin Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Zyxin

Zyxin Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Zyxin

Zyxin Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Antibody Pairs

Catalog No.    

ZYX (Human) IP-WB Antibody Pair

ZYX (Human) IP-WB Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

ZYX 293T Cell Transient Overexpression Lysate(Denatured)

ZYX 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ZYX (mGFP-tagged)-Human zyxin (ZYX), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, ZYX (mGFP-tagged)-Human zyxin (ZYX), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, ZYX (Myc-DDK-tagged)-Human zyxin (ZYX), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, ZYX (Myc-DDK-tagged)-Human zyxin (ZYX), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Zyx (GFP-tagged) - Mouse zyxin (cDNA clone MGC:65721 IMAGE:6808149), 200 uL, >10^7 TU/mL

Lenti ORF particles, Zyx (GFP-tagged) - Mouse zyxin (cDNA clone MGC:65721 IMAGE:6808149), 200 uL, >10^7 TU/mL  
200 µl / €1,170.00
  OriGene Technologies, Inc.

Lenti ORF particles, Zyx (Myc-DDK-tagged) - Mouse zyxin (cDNA clone MGC:65721 IMAGE:6808149), 200 uL, >10^7 TU/mL

Lenti ORF particles, Zyx (Myc-DDK-tagged) - Mouse zyxin (cDNA clone MGC:65721 IMAGE:6808149), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

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